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NCT Number: NCT06962878

Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars

Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients. One group assigned for placement of xenograft after molar extraction and immediate implant placement, while the other group received allograft as space-filling material.

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Key information

Conditions

Bone Volume Immediate Implant With Bone Graft

Age range

25 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with non-restorable mandibular molars
  • Both sexes with age range from 25 years to 40 years
  • Good oral hygiene
  • Adequate alveolar bone dimensions for implant replacement
  • Adequate bone volume after extraction to achieve primary stability of the immediate implant
  • Co-operative patient

Exclusion criteria

  • Patients with any systemic disease as uncontrolled diabetes or osteoporosis
  • Heavy smokers with smokers more than 10 cigarettes per day
  • Pregnancy
  • Patients with any signs of active infection or pus formation
  • Patients undergoing chemotherapy or radiotherapy, immunocompromised patients

Treatment and study plan

xenograft

Procedure

The jumping gap and surrounding space will be augmented and packed with Xenograft

Allograft

Procedure

The jumping gap and surrounding space will be augmented and packed with Allograft

Primary outcomes

  1. Horizontal bone thickness in millimeters

    Time frame: 6 months postoperative

    Two CBCT images will be taken, one immediately after surgery (baseline) and the other at 6 months post-surgically

Secondary outcomes

  1. Vertical bone height in millimeters

    Time frame: 6 months postoperative

    Two CBCT images will be taken, one 2 days after surgery (baseline) and the other at 6 months post-surgically

  2. Pain intensity

    Time frame: One week postoperative

    The pain will be recorded by participants at 1, 3, and 7 days after surgery using the Visual Analogue Scale (VAS), which ranges from 0 to 10. The minimum score is 0, indicating no pain, and the maximum score is 10, representing the worst possible pain. Higher scores on the VAS indicate worse outcomes in terms of pain experienced.

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed Mohamed Tawfik, BSc

CONTACT

[email protected]

+201095544285

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars: Randomized Clinical Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
May 8, 2025
Registry last updated
Aug 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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