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Completed

NCT Number: NCT06306105

Assessment of Anti-aging Efficacy of Marine Collagen Peptides

To assess the anti-aging efficacy of Marine Collagen Peptides on skin, hair and finger nails for human

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Key information

Conditions

Skin Condition Hair Fragility Nail Diseases Nails, Ingrown Skin Diseases Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chia Nan University of Pharmacy & Science

Pingtung City, 928, Taiwan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults aged above 18 years old

Exclusion criteria

  • Subjects who are not volunteers
  • Subjects who have been diagnosed with dermatitis, cirrhosis, and chronic kidney failure
  • Subjects who have known cosmetic, drug or food allergies.
  • Patients are taking medicine for chronic diseases
  • Subjects receiving treatments for scalp, hair transplant, and other scalp medical care in past 12 weeks.
  • Subjects getting a manicure and perm in past 12 weeks.
  • Female who is pregnant or nursing or planning to become pregnant during the course of the study.
  • Subjects receiving facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 12 weeks.
  • Students who are currently taking courses taught by the principal investigator of this trial.
  • Subjects are not willing to reveal the results of pictures after taking the product
  • Vegetarian.

Treatment and study plan

Marine Collagen Peptides

Dietary Supplement

consume 1 bottle per day

Other names: Coral club Promarine Collagen Tripeptides

Placebo drink

Dietary Supplement

consume 1 bottle per day

Primary outcomes

  1. The change of skin hydation

    Time frame: Change from Baseline skin skin hydation at 12 weeks

    Corneometer® CM825 (CK, Germany) was utilized to measure skin surface hydation. Units: arbitrary Corneometer® units 0-120.

  2. The change of skin wrinkles

    Time frame: Change from Baseline skin wrinkles at 12 weeks

    VISIA Complexion Analysis was utilized to measure skin wrinkles. Units: the amount of detectable wrinkles

  3. The change of skin elasticity

    Time frame: Change from Baseline skin elasticity at 12 weeks

    Cutometer® MPA580 was utilized to measure skin elasticity. Units: visco-elasticity in %.

  4. The change of skin collagen density

    Time frame: Change from Baseline skin collagen density at 12 weeks

    DermaLab® Series SkinLab Combo was utilized to measure skin collagen density. Units: arbitrary units

  5. The change of hair diameters

    Time frame: Change from Baseline hair diameters at 12 weeks

    Mitutoyo C/N293-100 was utilized to measure hair diameters. Units: millimeter

  6. The change of hair loss amount

    Time frame: Change from Baseline hair loss amount at 12 weeks

    Collect and measure the weight of loss hair. Units: gram

  7. The change of hair roots diameters

    Time frame: Change from Baseline hair roots diameters at 12 weeks

    Mitutoyo C/N293-100 was utilized to measure hair roots diameters. Units: millimeter

  8. The change of hair density

    Time frame: Change from Baseline hair density at 12 weeks

    Soft Plus was utilized to picture and observe hair density.

  9. The change of hair follicle strength

    Time frame: Change from Baseline hair follicle strength at 12 weeks

    Pull up the hair of the frontal bone, temporal bone and occipital bone (approximately 60 hairs/area) to assess the number of hair loss in each area. Units: the number of loss hair

  10. The change of thumbs nail color

    Time frame: Change from Baseline thumbs nail color at 12 weeks

    Chroma Meter MM500 was utilized to measure thumbs nail color. Units: L* index

  11. The change of nails appearence

    Time frame: Change from Baseline nails appearence at 12 weeks

    Picture taken was utilized to record and observe nails appearence.

  12. The change of nails growth

    Time frame: Change from Baseline marking position at 12 weeks

    Marking the position of middle fingers lunula was utilized to record and observe nails growth. Units: milimeter

  13. The degree of nails fragility

    Time frame: Change from Baseline nails fragility at 12 weeks

    Iron ruler was utilized to evaluate nails fragility. Picture taken was utilized to record and observe the change of nails fragility.

Secondary outcomes

  1. The change of self-assessment skin, hair, and nails condition

    Time frame: Change from Baseline skin, hair, and nails condition at 12 weeks

    A self-assessment questionnaire was collected and evaluate skin, hair, and nails condition

Sponsors and collaborators

Lead sponsor

TCI Co., Ltd.

Industry

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Mar 12, 2024
Registry last updated
Sep 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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