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NCT Number: NCT07254195

Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients

Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. However, after hospitalization, access to intensive rehabilitation is limited, due to geographical and mobility constraints, and the lack of reimbursement for private occupational therapy.

Telerehabilitation, using digital technologies, can overcome these difficulties by offering interactive, accessible rehabilitation at home. Studies show that its effectiveness is comparable to that of clinical rehabilitation.

Our study therefore proposes to evaluate the feasibility and effects of a home-based telerehabilitation program using the MindMotion GO device (MindMaze). This 12-week program aims to provide an additional intensive dose of rehabilitation to the standard of care, with 300 minutes of weekly active therapy, planned and monitored remotely by a therapist.

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Key information

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hopital Henry Gabrielle

Saint-Genis-Laval, Lyon, 69230, France

Location status: Recruiting

Location contact

Jacques LUAUTÉ, MD, PhD

CONTACT

[email protected]

4 78 86 50 64 ext. +33

About this study

Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. However, after hospitalization, access to intensive rehabilitation is limited, due to geographical and mobility constraints, and the lack of reimbursement for private occupational therapy.

Telerehabilitation, using digital technologies, can overcome these difficulties by offering interactive, accessible rehabilitation at home. Studies show that its effectiveness is comparable to that of clinical rehabilitation.

Our study therefore proposes to evaluate the feasibility and effects of a home-based telerehabilitation program using the MindMotion GO device (MindMaze). This 12-week program aims to provide an additional intensive dose of rehabilitation to the standard of care, with 300 minutes of weekly active therapy, planned and monitored remotely by a therapist. It combines synchronous (1time a week with a therapist) and asynchronous (autonomous) sessions.

This program is integrated into the post-stroke care pathway by facilitating the transition from hospital to home, without prolonging hospitalization or increasing face-to-face sessions.

The study will be a single-center randomized controlled trial, targeting patients in the sub-acute and chronic stages of stroke.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Hospitalized for a first ischemic or hemorrhagic stroke
  • Stroke occurrence more than 30 days prior
  • Presenting motor deficits affecting the upper limb, with or without involvement of the lower limb
  • Able to follow the instructions of the home program using the MindMotion GO device
  • Having at home an accessible email address, an Internet connection with password, a smartphone, a screen or TV with HDMI input (Full HD 1080p resolution), and a free space of approximately 1 m x 2.5 m in front of the screen
  • Ability to sit without assistance
  • Patient agreeing to participate in the study by signing an informed consent form
  • Affiliated with, or entitled to, a social security scheme

Exclusion criteria

History of stroke

  • Neurological pathology other than stroke
  • Patient with uncontrolled epilepsy or seizure disorder
  • Cardiac disease limiting exercise
  • Pain limiting rehabilitation dose
  • Major comprehension problems or severe psychiatric and/or cognitive disorders that could compromise understanding of the protocol and the smooth running of the study.
  • Uncorrected hearing or visual deficits
  • Severe apraxia
  • Severe memory impairment
  • Severe unilateral spatial neglect
  • Total plegia of affected limb
  • Pregnant, parturient or breast-feeding women
  • Persons deprived of their liberty by judicial or administrative decision
  • Persons admitted to a health or social institution for purposes other than research
  • Adults under legal protection (guardianship, curatorship)
  • Subjects participating in other intervention research.

Treatment and study plan

Telerehabilitation program using the MindMotion GO device

Device

In parallel to the standard of care, patients will participate in a 12-weeks telerehabilitation program using the MindMotion GO device.

MindMotion GO is a digital therapy device that offers a catalog of interactive games designed specifically for patients with neurological injuries.

During the telerehabilitation program, patients will aim to achieve at least 300 minutes of active therapy per week. They will have 1 synchronous session per week in the clinic or remotely by videoconference with a therapist (PT or OT). Patients are expected to carry out the other planned sessions independently at home. The activity schedule will be drawn up by a remote therapist each week and will be personalized for each patient.

Primary outcomes

  1. Variation in the Goal Attainment Scale (GAS) score.

    Time frame: Baseline, at 8, 20, 32 and 44 weeks

    The GAS is used to measure achievement of individual goals. GAS goals will be set for each participant before the start of the intervention. Achievement of each objective will be rated on a 5-point scale: -2 (patient's initial, pre-intervention level), -1 (progress towards goal, without complete attainment), 0 (expected level), +1 (goal achieved better than expected), +2 (best hoped-for result).

Study contacts

Contact information is provided by the study sponsor or research team.

Anne-Laure CHARLOIS

CONTACT

[email protected]

478 86 51 13 ext. +33

Jacques LUAUTÉ, MD

CONTACT

[email protected]

4 78 86 50 64 ext. +33

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Official study title

Intensive Motor Rehabilitation of Stroke Patients: Evaluation of a Telerehabilitation Program

Acronym: REACT-AVC

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Nov 28, 2025
Registry last updated
Mar 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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