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OpenTrials
Completed

NCT Number: NCT00596440

Assessment of a Teachable Moment for Smoking Cessation

A teachable moment (TM) refers to life events or transitions, such as physician visits, early detection screening feedback, pregnancy, and hospitalization for, and diagnosis of, disease, that inspire health behavior change. Despite strong intuitive appeal of the TM concept and over 150 studies of interventions implemented in a TM, there has been little investigation of the influence of TMs for smoking, particularly for promoting smoking cessation among those indirectly affected by a TM (e.g., relatives of cancer patients). This prospective observational study using a matched-group design will assess whether a lung cancer diagnosis increases enrollment in a smoking cessation program and cessation, and reduces smoking, among the patient's relatives/spouse who smoke. We will compare enrollment in a cessation program and cessation and smoking rates in 2 groups of smokers: 1) relatives/spouses of newly-diagnosed lung cancer patients, and 2) relatives/spouses of patients with an orthopedic condition. We will also explore mediators and moderators of a lung cancer diagnosis as a TM. This study could clarify the TM concept for smoking cessation, shed light on the underlying mechanisms of TMs, and guide future development and implementation of TM-based smoking cessation interventions.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • A relative (i.e., sibling, parent, child, grandparent, aunt, uncle, cousin) or spouse of a newly-diagnosed lung or head and neck cancer patient or orthopedic patient (e.g., arthritis, bone and joint infection, foot and ankle conditions, hand, wrist, and elbow conditions such as carpal tunnel syndrome, shoulder and elbow conditions, such as rotator cuff injury, and knee conditions, such as ligament damage repair);
  • A regular smoker (i.e., smoke 10 cigarettes/day on average);
  • Able to use NRT (see contraindications under Key Exclusion Criteria);
  • Age 18 or older (to use NRT); and
  • Living within ~50 miles of PENN (to allow for meetings at PENN).

Exclusion criteria

  • Cannot communicate in English;
  • Have current alcohol abuse/dependence;
  • Are or have been diagnosed with cancer, asthma, HIV, emphysema, or COPD;
  • Have a current medical problem for which NRT is contraindicated such as uncontrolled hypertension (> 150 over 90), unstable angina, heart attack or stroke within the past 6 months, and liver and/or kidney failure in the last 6-months;
  • Currently use monoamine oxidase inhibitors or benzodiazepines, anti-psychotics, and antidepressants, including bupropion;
  • Are allergic to adhesive tape or latex, and
  • Are a female who is pregnant or nursing.

Treatment and study plan

Transdermal Nicotine Patch

Drug

8 weeks; 4 weeks of 21mg, 2 weeks of 14mg, and 2 weeks of 7mg.

Primary outcomes

  1. Accrual Rate (Eligibility Visit)

    Time frame: week zero

    Show rate to eligibility visit

Secondary outcomes

  1. Smoking Cessation Rate

    Time frame: week nine

  2. Show Rate at First Treatment Session

    Time frame: week one

Sponsors and collaborators

Lead sponsor

University of Pennsylvania

Other

Collaborators

  • National Institutes of Health (NIH)

Registry information

Acronym: TM

Important dates

Study start
2007
Primary completion
2011
Study completion
2012
First posted
Jan 17, 2008
Registry last updated
Aug 28, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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