Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients

The purpose of this observational study is to understand the impact of polypharmacy on the prognosis of elderly patients with chronic diseases. The main research question it aims to address is:

Does polypharmacy affect the prognosis of elderly patients with chronic diseases? Elderly patients with chronic diseases will be asked to complete online survey questions regarding their disease prognosis over a 2-year period.

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Key information

Conditions

Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Body Weight Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Chronic Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease (COPD) Coronary Disease Diabete Mellitus Diabetes Mellitus Disease Attributes Dyslipidemias Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Glucose Metabolism Disorders Heart Diseases Heart Failure Hyperlipidemia Hyperlipidemias Hypertension Kidney Diseases Lipid Metabolism Disorders Lung Diseases Lung Diseases, Obstructive Male Urogenital Diseases Metabolic Diseases Myocardial Ischemia Nervous System Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Obesity &Amp; Overweight Overnutrition Overweight Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Renal Insufficiency Renal Insufficiency, Chronic Respiratory Tract Diseases Signs and Symptoms Stroke Urogenital Diseases Urologic Diseases Vascular Diseases

Age range

65 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Xijing Hospital

Xi'an, Shaanxi, 710032, China

Location status: Recruiting

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients aged 65 years or older with at least one chronic disease

Exclusion criteria

Patients without chronic diseases
Patients refused to participate in the study
Patients with unstable vital signs

Treatment and study plan

Primary outcomes

Assessing the current status of polypharmacy in elderly patients with chronic diseases in Shaanxi Province via cluster sampling questionnaire survey

Time frame: Start from enrollment to the end of the study at 2 years.

A cluster sampling method was used to conduct a survey on elderly patients with chronic diseases in Shaanxi Province. A questionnaire survey was conducted in different regional locations to collect detailed medication information from patients, such as the number of chronic diseases (types), the types of medications used (types), specific drug names, medication costs (yuan), and duration of medication use (months). Medication habits, such as whether the medication is prescribed by a hospital, purchased from a pharmacy, recommended by friends, or promoted through advertisements, etc. Specific items include concerns about drugs and current physical discomforts. A 5-point Likert scale was adopted, where 1 point indicates "strongly disagree" and 5 points indicate "strongly agree". After questionnaire collection, combined with Beers, STOPP/START, and Chinese elderly PIM criteria, a polypharmacy evaluation and management strategy for these patients was developed.

Study contacts

Contact information is provided by the study sponsor or research team.

Ming Yuan, MD, PhD

CONTACT

[email protected]

029-84775188

Sponsors and collaborators

Lead sponsor

Xijing Hospital

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2026
Study completion: 2027
First posted: Sep 18, 2025
Registry last updated: Sep 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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