40mg oral iron dosing
Dietary SupplementParticipants will receive a single morning oral dose of iron as Fe57-labelled ferrous sulfate
NCT Number: NCT06657677
Serum ferritin is a key indicator of body iron stores and is widely used in monitoring iron status. However, oral iron doses can acutely elevate SF levels, potentially biasing assessments of iron stores during supplementation. This study aims to investigate the extent and duration of the acute iron-induced effect on serum ferritin, as well as its protein characteristics, following the administration of a single iron dose
Looking for future studies?
Notify Me18 year–45 year
Female
Interventional
Not applicable
ETH Zurich, Zurich, Canton of Zurich, Switzerland
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Participants will receive a single morning oral dose of iron as Fe57-labelled ferrous sulfate
Participants will receive a single morning oral dose of iron as Fe57-labelled ferrous sulfate
Participants will receive a single morning oral dose of iron as Fe57-labelled ferrous sulfate
Time frame: study day 1
Serum ferritin concentration
Time frame: study day 7
Serum ferritin concentration
Time frame: study day 0
C-reactive protein concentration in serum
Time frame: study day 0
Serum ferritin concentration
Time frame: study day 6
Serum ferritin concentration
Time frame: study day 14
Serum ferritin concentration
Time frame: study day 5
Serum ferritin concentration
Time frame: study day 4
Serum ferritin concentration
Time frame: study day 3
Serum ferritin concentration
Time frame: study day 2
Serum ferritin concentration
Time frame: study day 0
alpha(1)-acid-glycoprotein concentration in serum
Time frame: study day 0
soluble transferrin receptor in serum
Time frame: study day 0
Hemoglobin concentration
Time frame: study day 0
serum iron concentration in circulation
Time frame: study day 1
serum iron concentration in circulation
Time frame: study day 2
serum iron concentration in circulation
Time frame: study day 3
serum iron concentration in circulation
Time frame: study day 4
serum iron concentration in circulation
Time frame: study day 5
serum iron concentration in circulation
Time frame: study day 6
serum iron concentration in circulation
Time frame: study day 7
serum iron concentration in circulation
Time frame: study day 14
serum iron concentration in circulation
Time frame: study day 0
shift in stable iron isotopes in serum ferritin
Time frame: study day 2
shift in stable iron isotopes in serum ferritin
Time frame: study day 7
shift in stable iron isotopes in serum ferritin
Time frame: study day 0
Proteomics
Time frame: study day 2
Proteomics
Time frame: study day 7
Proteomics
Time frame: study day 14
Erythrocyte iron incorporation of stable iron isotope
Jessica Rigutto
Other
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women.
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04228627
Anemia, Hematologic Diseases
Lahore, Punjab Province, Pakistan
View Trial DetailsNCT05869422
Iron Deficiencies, Iron Deficiency (Without Anemia)
Zurich, Canton of Zurich, Switzerland
View Trial DetailsNCT05467423
Iron Deficiencies, Iron Deficiency (Without Anemia)
Zurich, Switzerland
View Trial DetailsNCT06021171
Anemia, Anemia, Hypochromic
Wilkes-Barre, Pennsylvania, United States
View Trial Details