University of Basel, Division of Cognitive Neuroscience
Basel, Canton of Basel-City, 4055, Switzerland
Location status: Recruiting
NCT Number: NCT07191288
A Four-Arm RCT, testing the acute effects of a Virtual Reality (VR)- based slow-paced breathing intervention on subjective and physiological markers of stress. The investigator hypothesize that combining slow breathing with immersive, mystical-type VR elements will result in the greatest stress reduction.
Interested in participating?
Request Info18 year–35 year
All sexes
Interventional
Not applicable
Basel, Canton of Basel-City, 4055, Switzerland
Location status: Recruiting
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The VR-based slow-paced breathing application is designed to provide rewarding biofeedback for a specific breathing pattern characterized by prolonged exhales. As users extend their exhales, a veil of fog gradually lifts, introducing a mystical type experience. Over time, users are rewarded with a full 360-degree panoramic view of the beautiful nature scene, accompanied by relaxing music. After approximately 5 minutes of prolonged exhales, the nature scene responds to the user's breathing by slowing down, with falling snowflakes moving more slowly, further enhancing the mystical atmosphere. This intervention was designed to be visually captivating, mystically evocative, and emotionally engaging. Duration: 10 minutes.
Users will experience the gradual unveiling of a beautiful natural landscape as the fog lifts, and eventually, the scene slows down similar to the VR Breathing+Mystical condition. However, this application does not provide any biofeedback or breathing instructions. Users are invited to passively observe the unfolding experience, immersing themselves in the environment for 10 minutes. Relaxing music accompanies the scene. This condition relies solely on the immersive and aesthetic qualities of the virtual environment to potentially induce relaxation.
In this conventional breathing intervention, participants will be instructed to follow a slow-paced breathing pattern guided by a simple visual cue (an expanding and contracting circle) displayed on a computer screen for 10 minutes. This condition is designed to guide slow-paced breathing without incorporating any rewarding elements.
In the control condition, participants will watch a neutral documentary for 10 minutes in VR. This condition is used to control for the effects of the immersive VR experience. It does not include any components related to guided breathing or mystical-type content, or any form of rewarding elements.
Time frame: Assessed before and after the 10-minute interventions.
Subjective stress measured using visual analogue scales (VAS) on a computer
Time frame: Assessed before and after the 10-minute interventions.
Mood measured using visual analogue scales (VAS) on a computer.
Time frame: Assessed before and after the 10-minute interventions.
Anxiety measured using visual analogue scales (VAS) on a computer.
Time frame: Assessed before and after the 10-minute interventions.
Relaxation measured using visual analogue scales (VAS) on a computer.
Time frame: Assessed during the 10-minute interventions.
Physiological responses measured via Electrodermal Activity.
Time frame: Assessed during the 10-minute interventions.
Physiological responses measured via Piezoelectric Sensor (detecting variations in abdominal movement during respiration).
Time frame: Assessed during the 10-minute interventions.
Blood volume pulse measured via Photoplethysmography.
Time frame: Assessed during the 10-minute interventions.
Heart rate outcomes (e.g., HR, HRV) measured via Electrocardiogram.
Time frame: Assessed after the 10-minute interventions.
Perceived mysticality assessed using the Mystical Experience Questionnaire-30 questionnaire.
Time frame: Assessed after the 10-minute interventions.
Average user experience measured via visual analogue scales (VAS) on a computer.
Contact information is provided by the study sponsor or research team.
Prof. Dominique de Quervain, MD
Other
Assessing the Acute Effects of Virtual Reality Interventions on Stress: A Four-Arm RCT
Acronym: VR_Stress_25
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