Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07523815

Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Guided Implant Placement

The AI assisted CAD/CAM workflow will be adopted for the treatment planning and guide design generation with the aim of comparing precision of implant placement with conventional digital workflow.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Faculty of Dentistry - Cairo University

Cairo, Manial, Egypt

Location status: Recruiting

Location contact

Nehal I Shobair, Teacher

CONTACT

[email protected]

00201063666985

About this study

The study will be conducted in Oral and Maxillofacial Department, Faculty of Oral and Dental Medicine, Cairo University.After patient's selection, the CBCTs will be captured for the edentulous area along with a full arch PVS impression for the upper and lower arches. The patients will then be randomly allocated into two groups. Group I, AI assisted group, the AI assisted workflow will be adopted for the treatment planning and guide design generation. Then, the surgical guide with the embedded sleeve will be designed and 3D printed. For Group II, Static CAIS group, the virtual implant planning for all patients will be done by one qualified experienced dentist in implant dentistry. Then, the surgical guide with the embedded sleeve will be designed and 3D printed with computer-aided design/computer-aided manufacturing (CAD/CAM) technology. The guides will then be disinfected to be ready for the surgical procedure. All patients will be administered 400 mg Ibuprofen 1 hour prior to surgery and will be instructed to rinse with a 0.12% Chlorhexidine solution for 60 s. After administration of local anesthesia,implant placement will be performed according to the allocated treatment protocol by one experienced surgeon. The following process will be the same for both guided techniques. The fit and stability of the 3D surgical guide will be verified prior to the surgery through tactile inspection and confirming the fit through the inspection window areas of the guide on top of the teeth. Implant bed preparations and implant insertions will be done through the 3D surgical guide in accordance with the manufacturer's fully guided surgical protocol. The drilling sequence will be followed as needed for each case. The implant will be placed via a fully guided implant placement regimen and a healing abutment will be placed for transmucosal healing. Wound suturing will be performed as needed and all the patients will receive postoperative instructions and will be appointed for a follow up and suture removal visit one week postoperatively. All patients will have an immediate postoperative CBCT.

The postoperative medications list will include systemic antibiotics (1 g of amoxicillin, twice a day) and an analgesic (500 mg of mefenamic acid, three times a day) for 5 days. For patients who were allergic to penicillin, 300 mg of clindamycin will be prescribed three times a day.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Kennedy class III partially edentulous patient with or without modifications.
  • Patients who need single implant posterior site delayed implant placement.
  • Patients above 18 and below 60 years of age.
  • Natural healthy neighboring teeth without need of new restorations.

Exclusion criteria

  • Patients with D4 bone density.
  • Patients with known systemic or local diseases or treatments which can affect normal tissue healing.
  • Patients who are heavy smokers.
  • Presence of signs of active infection or pus formation.
  • Patients with a need for implants in the anterior region.
  • Additional oral surgery in the region of interest.
  • Need For Bone grafting.
  • Pregnant and/or lactating women

Treatment and study plan

AI assisted implant placement

Procedure

the AI assisted workflow will be adopted for the treatment planning and guide design generation. Then, the surgical guide with the embedded sleeve will be designed and 3D printed.

Conventional computer guided implant placement

Procedure

The virtual implant planning for all patients will be done by one qualified experienced dentist in implant dentistry. Then, the surgical guide with the embedded sleeve will be designed using the conventional CAD steps for static guide design and 3D printed with computer-aided design/computer-aided manufacturing (CAD/CAM) technology.

Primary outcomes

  1. Linear Discrepancy

    Time frame: Immediate post operative

    The linear implant position discrepancy between the plan and the actual implant position in millimeters will be assessed using a specialized software.

  2. Angular Discrepancy

    Time frame: Immediate post operative

    The angular implant position discrepancy between the plan and the actual implant position in degrees will be assessed using a specialized software.

  3. CAD Timing

    Time frame: Immediate post operative

    The time elapsed for AI assisted CAD, will be compared to time elapsed during conventional CAD workflow in seconds using a stopwatch.

Study contacts

Contact information is provided by the study sponsor or research team.

Nehal IA Shobair, PhD

CONTACT

[email protected]

00201063666985

Sandra Moussa El Tarzi, BDS

CONTACT

[email protected]

+201226665141

Sponsors and collaborators

Lead sponsor

Sandra Moussa Botros El Tarzi

Other

Registry information

Official study title

Assessment of the Accuracy of Artificial Intelligence Assisted Workflow Versus Conventional Workflow in Computer Guided Implant Placement: A Randomized Controlled Clinical Trial.

Acronym: Implant

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 13, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.