Kocaeli University Faculty of Dentistry
Kocaeli, Basiskele, 41190, Turkey (Türkiye)
NCT Number: NCT04645888
Articaine is a common local anesthetic used in oral surgery and belongs to the amide group of it has fast onset with little side effects. Bupivacaine is preferred in prolonged surgical procedures with its long duration of action and residual analgesic effect.
The aim of this study was to evaluate the anesthetic, analgesic, hemodynamic effects of 4% articaine and 0.5% bupivacaine in extraction of impacted mandibular third molar teeth in intraoperative and postoperative periods. Hemodynamic parameters, onset of anesthetic action, total amount, intraoperative comfort, intraoperative bleeding, duration of postoperative anesthesia and analgesia, rescue analgesic use, maximum incisal opening and postoperative pain at 6th, 12th, 24th, 48th and 72th hours and 7th day using a visual analogue scale be evaluated.
Looking for future studies?
Notify Me18 year–25 year
All sexes
Interventional
Not applicable
Kocaeli, Basiskele, 41190, Turkey (Türkiye)
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Surgical extraction of İmpacted tooth
Time frame: 60 minutes
Systolic and diastolic blood pressure, cardiac rate and blood oxygen saturation level were monitored using a patient monitor before beginning of the surgery (T1), 1 min later following the anesthesia (T2) and immediately after the surgery (T3).
Time frame: 1 week
Postoperative pain was evaluated by Visual Analogue Scale (VAS) ranging from 0 to 10 and patients were instructed to complete the scale in 6th, 12th, 24th, 48th and 72th hours and 7th day postoperatively.
Time frame: 7days
Maximal incisal opening (MIO) measured with ruler preoperatively and at the 7th day.
Time frame: 60 minutes
Duration of the surgery, which was determined by the time between the first incision to last suture was recorded.
Time frame: 10 minutes
Onset of anesthetic action was be determined by the first sign of numbness of the ipsilateral lower lip, tongue and alveolar mucosa,
Time frame: 60 minutes
The time between the first incision and the last suture was evaluated as operation time.
Time frame: 60 minutes
The quality of the anesthesia was evaluated by the surgeon which was based on a 3- point category rating scale: Grade 1: no discomfort reported by the patient during the surgery; Grade 2: any discomfort reported by patient during the surgery, without the need of additional anesthesia; Grade 3: any discomfort reported by patient during the surgery, with the need of additional anesthesia.
Time frame: 60 minutes
Intraoperative bleeding was rated by the surgeon which based on a 3-point category rating scale as: Grade 1: minimal bleeding; Grade 2: normal bleeding; Grade 3: excessive bleeding.
Time frame: 60 minutes
Surgical difficulty was determined by modified Parant scale as follows:
Grade 1: extraction with forceps only; Grade 2: extraction by osteotomy; Grade 3: extraction by osteotomy and coronal section; Grade 4: complex procedures (root section).
Time frame: 6 hours
Duration of the postoperative anesthesia be determined by the absence of sensibility of ipsilateral lower lip, tongue and alveolar mucosa and duration of the postoperative analgesia determined by the time from the end of the operation to the first naproxen sodium intake.
Kocaeli University
Other
Evaluation of the Effects of Articaine and Bupivacaine in Impacted Third Molar Tooth Surgery
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07436546
Impacted Third Molar, Impacted Third Molar Tooth
Rohtak, Haryana, India
View Trial DetailsNCT06244797
Impacted Third Molar Tooth
Tokat Province, Kaleardı Neighbourhood, Turkey (Türkiye)
View Trial DetailsNCT07333963
Impacted Third Molar Tooth, Stomatognathic Diseases
Bytom, Silesian Voivodeship, Poland
View Trial DetailsNCT03893175
Acute Pain, Impacted Third Molar Tooth
Philadelphia, Pennsylvania, United States
View Trial Details