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Completed

NCT Number: NCT07408323

Arthroscopic Transtibial Pullout Suture Repair Versus Suture Anchor Repair in Posterior Root Tear of the Medial Meniscus

The menisci play a fundamental role in maintaining normal knee biomechanics by distributing load, absorbing shock, providing stability, and facilitating joint lubrication. Damage to the meniscus, particularly root tears, disrupts hoop tension and leads to altered joint loading patterns. This condition accelerates cartilage degeneration and predisposes patients to early-onset osteoarthritis, especially when untreated or inadequately managed.

Posterior root medial meniscus tears (PRMMTs) have gained increasing clinical attention in the past two decades. These injuries are biomechanically equivalent to a total meniscectomy because they cause extrusion of the meniscus and loss of its load- sharing capacity. PRMMTs typically affect middle-aged and older patients, often associated with degenerative changes, but can also occur in younger populations following trauma or high-impact activities.

The clinical presentation of PRMMTs is often subtle, with patients experiencing posterior knee pain, mechanical symptoms, and joint line tenderness. Magnetic resonance imaging (MRI) remains the gold standard for diagnosis, with characteristic findings such as the "ghost sign" and meniscal extrusion beyond 3 mm. However, diagnosis is frequently delayed, contributing to the progression of cartilage degeneration by the time of surgical intervention.

Several risk factors have been identified, including female gender, obesity, varus malalignment, and increased posterior tibial slope. These factors not only predispose patients to PRMMTs but also influence the prognosis following surgical repair. Given the high prevalence of these risk factors, especially in populations with rising obesity and osteoarthritis incidence, effective treatment strategies have become essential.

Surgical repair techniques have evolved significantly to restore hoop stresses and improve long-term outcomes. Two widely practiced arthroscopic methods are the transtibial pullout suture repair and the suture anchor repair. Both aim to reattach the meniscal root to its anatomical footprint, thereby restoring biomechanics and delaying degenerative progression.

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Key information

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine, for Girls, Al-Zhar University, Egpyt

Giza, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 20 and 50 years, both sexes.
  • Acute or degenerative posterior root tear of the medial meniscus confirmed by MRI.
  • Isolated medial meniscus root tear or tear associated with anterior cruciate ligament (ACL) injury.
  • Willingness to participate and sign informed consent.

Exclusion criteria

  • Refusal to participate.
  • Knee joint malalignment (varus/valgus) confirmed clinically and radiologically.
  • Osteoarthritis grade III or IV according to Kellgren-Lawrence classification.
  • Irreparable or severely degenerated crushed meniscus.
  • Prior ipsilateral knee fracture, infection, or tumor.
  • Patients were deemed unfit for surgery or anesthesia.

Treatment and study plan

Arthroscopic Transtibial Pullout Suture Repair

Procedure

Patients will have arthroscopic transtibial pullout for their Posterior Root Tear of the Medial Meniscus according to the description in the protocol

Suture Anchor Repair

Procedure

patients will had this procedure according to the description in the protocol

Primary outcomes

  1. subjective functional improvement assessed via the Arabic validated form of the Lysholm score.

    Time frame: 1 year

    The Lysholm score is a 100-point, patient-reported questionnaire evaluating knee ligament and meniscus injury, with higher scores indicating better function. Score of 95-100 indicate excellent function, 84-94 indicate good function, 65-83 indicate fair function, while less than 65 indicates poor function

  2. subjective functional improvement assessed via the Arabic validated form of the International Knee Documentation Committee 2000 score

    Time frame: 1 year

    The International Knee Documentation Committee 2000 score is a 19-item patient-reported outcome measure scoring symptoms, activity, and function on a 0-100 scale. Higher scores indicate better knee function and fewer symptoms.

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Arthroscopic Transtibial Pullout Suture Repair Versus Suture Anchor Repair in Posterior Root Tear of the Medial Meniscus: An Open-Label, Blinded-Endpoint, Randomized, Controlled Trial.

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Feb 13, 2026
Registry last updated
Feb 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.