Arterial Stiffness Index as a Predictor of Surgically Correctable Primary Aldosteronism

Secondary objectives are to investigate whether aortic stiffness predicts cardiovascular , operative and postoperative morbid-mortality at 1 year, to evaluate the benefit of adrenalectomy in patients with primary aldosteronism due to unilateral adrenal hyperplasia and in patients with aldosterone producing adenoma associated with controlateral adrenal morphological abnormalities, and to participate to a national DNA repository of patients with primary aldosteronism.

Inclusion criteria

• patients with a surgically correctable primary aldosteronism due to an aldosterone producing adenoma or an unilateral adrenal hyperplasia
• primary aldosteronism demonstrated by hormonal essays
• hight resolution adrenal CT scan
• operative decision based on the usual criteria of the different referent centers

Exclusion criteria

• patient's refusal to undergo the surgery or to participate in the study
• the patients with PA due to bilateral adrenal hyperplasia or with idiopathic primary aldosteronism, and patients with a biochemical diagnosis of PA without evidence for a lateralized aldosterone excess.