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NCT Number: NCT04367857

ARMOR Study: COVID-19 Seroprevalence Among Healthcare Workers

The novel coronavirus (SARS-CoV-2) has spread all around the world and testing has posed a challenge globally. Health care providers are highly exposed and are an important group to test. On top of these concerns, health care workers are also stressed by the needs on responders in the COVID-19 crisis. The investigators will look at different ways to measure how common COVID-19 is among health care workers, how common is the presence of antibodies by serological tests (also known as serostatus). The investigators will describe health worker mental and emotional well-being and their coping strategies in their institutional settings. Lastly, the investigators will describe how knowing serostatus can affect individuals' mental and emotional well-being and how to cope in the midst of the COVID-19 response. This will help to how to better test and help healthcare workers in the COVID-19 pandemic and prepare for possible future outbreaks.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

NewYork-Presbyterian Hosptial/Columbia University Irving Medical Center

New York, 10032, United States

Location status: Recruiting

Location contact

Brett Gray

CONTACT

About this study

The rapid spread of the novel coronavirus SARS-CoV-2 has resulted in pandemic levels and a global challenge in diagnosing infection. Diagnosing infection, defining recovery and immunity has been challenging. Health care providers in particular are very interested in knowing their status as they are highly exposed, and if infectious, can potentially transmit infection nosocomially (in the healthcare workplace setting) and to their household. In addition to understanding their exposure risk, infectious period, and immunity status, health care workers are reporting high levels of psychosocial distress including anxiety and burnout. The investigators aim to assess the baseline and cumulative seroprevalence of SARS-CoV-2 among health care workers using both quantitative and qualitative serological assays; describe psychosocial well-being and coping strategies among health workers in their institutional settings and describe how knowledge of one's serostatus affect psychosocial well-being, and coping strategies. Findings from this study will inform; 1) use of serological assays and testing algorithms, and 2) approaches to manage psychosocial stress for healthcare workers.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age or older
  • NewYork-Presbyterian (NYP) healthcare personnel employee or affiliate
  • Understands and reads English

Exclusion criteria

  • Younger than 18 years of age
  • Mentally and/or physically unable to complete study requirements

Treatment and study plan

COVID-19 Serology

Other

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

Health Care Worker Survey

Behavioral

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Primary outcomes

  1. Proportion seropositive

    Time frame: Up to 12 months after collection visit

    Percentage of health care workers with positive serological markers to describe patterns in exposure, re-infection, clinical symptom, serological responses among health care workers based on their baseline serological status over a one year period.

Study contacts

Contact information is provided by the study sponsor or research team.

Brett Gray

CONTACT

[email protected]

212-305-1570

Sponsors and collaborators

Lead sponsor

Columbia University

Other

Registry information

Official study title

SARS-CoV-2 Seroprevalence Among Healthcare Workers: ARMOR Study Demonstration Project

Important dates

Study start
2020
Primary completion
2027
Study completion
2027
First posted
Apr 29, 2020
Registry last updated
Apr 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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