ARC in Hemorrhagic Stroke

To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.

Completed

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Key information

Conditions

Hemorrhagic Stroke Augmented Renal Clearance Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Stroke Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of North Carolina Hospitals

Chapel Hill, North Carolina, 27599, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults ≥ 18 years
Patients with hemorrhagic stroke
Anticipated length of stay in the neuroscience intensive care unit > 48 hours
Informed consent provided by the patient or by the patient's designated medical proxy

Exclusion criteria

Pregnancy
Patients with pre-existing renal dysfunction (chronic kidney disease stages 3 - 5)
Patients receiving renal replacement therapy
Patients with an admission serum creatinine > 1.4 mg/dL
Patients with non-aneurysmal subarachnoid hemorrhage
Patients with history of nephrectomy or body mass index < 18 kg/m2

Treatment and study plan

No intervention

Other

No interventions

Primary outcomes

To describe the onset, magnitude, and change over time of ARC in patients with hemorrhagic stroke

Time frame: Over neurosciences intensive care unit stay

Daily 8-hour urine collections will be performed to directly measure creatinine clearance up to ICU discharge

Sponsors and collaborators

Lead sponsor

University of North Carolina, Chapel Hill

Other

Registry information

Official study title

Augmented Renal Clearance in Hemorrhagic Stroke Patients Admitted to the Neurosciences Intensive Care Unit

Important dates

Study start: 2015
Primary completion: 2015
Study completion: 2015
First posted: Mar 11, 2015
Registry last updated: Dec 2, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed