2nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang, China
NCT Number: NCT05902689
In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the Bio-Oss Collagen underwent alveolar ridge preservation using Bio-Oss Collagen and the Sticky Bone group using Sticky Bone, to verify the application of Bio-Oss Collagen and Sticky Bone in alveolar ridge preservation
This study is active but is not currently recruiting participants.
Notify Me18 year–70 year
All sexes
Interventional
Not applicable
Hangzhou, Zhejiang, China
Within 6 months after tooth extraction, the remaining alveolar ridge undergoes varying degrees of absorption, resulting in a decrease in horizontal width and vertical height of the alveolar ridge. The three-dimensional size change of the alveolar socket may affect the implantation of later implants and cause aesthetic and functional problems. Alveolar ridge preservation can maintain the volume of the alveolar socket, prevent soft tissue from growing into undesirable positions, slow down the absorption of the alveolar ridge to some extent, promote new bone formation, and maintain the shape of the extraction socket. This is crucial for later implant treatment for missing teeth. In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the Bio-Oss Collagen group underwent alveolar ridge preservation using Bio-Oss Collagen and the Sticky Bone group using Sticky Bone, respectively, to verify the application of Bio-Oss Collagen and Sticky Bone in alveolar ridge preservation
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Alveolar ridge preservation with bio-oss collagen is a surgical method that reduces or limits the physiological resorption of alveolar bone after tooth extraction by implanting bio-oss collagen in the socket and covering the biological barrier membrane.
Alveolar ridge preservation with sticky bone is a surgical method that reduces or limits the physiological resorption of alveolar bone after tooth extraction by implanting sticky bone in the socket and covering the biological barrier membrane.
Time frame: baseline (before the surgery) and six months
Changes in horizontal ridge widths at 1, 3, and 5 mm below the ridge crest
Time frame: baseline (before the surgery) and six months
Changes in the vertical heights of the ridge at the buccal and lingual crest areas
Time frame: baseline (before the surgery) and six months
Thicknesses of the keratinized gingiva at 2 and 4mm below the highest point of the gingiva
Time frame: baseline (before the surgery) and six months
width of the keratinized gingiva
Time frame: six months
percentages of newly formed bone and residual bone substitute material in histologic sections
Time frame: six months postoperative
Time frame: six months postoperative
Time frame: at baseline
Time frame: one week post-surgery
Time frame: at implant placement and one year after crown placement
Changes in buccolingual thickness of the peri-implant mucosa at 2 mm apical to the mucosal margin
Time frame: at crown placement and one year after crown placement
Changes in marginal bone level
Time frame: at implant placement and one year after crown placement (T6).
Changes in peri-implant buccal bone thickness at 2 mm apical to the implant shoulder
Time frame: one year after crown placement
Bleeding on probing and probing pocket depth
Second Affiliated Hospital, Zhejiang University, School of Medicine
Other
Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation: A Randomized Controlled Clinical Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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