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NCT Number: NCT05424978

Application of Standardized Green Channel Treatment System for Ischemic Stroke in Xi 'an

Objective: To observe the practical application of the standardized green channel treatment system for stroke in Xi 'an in the real world. Methods: Clinical data and information of patients with acute ischemic stroke who received standardized green channel treatment for stroke were collected, and a multicenter observational clinical study was carried out in the real world to evaluate the prognosis, mortality, incidence of asymptomatic and symptomatic cerebral hemorrhage, incidence of pneumonia, and recurrence rate of stroke after 90 days.

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Key information

Conditions

Acute Ischemic Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Endovascular Treatment Ischemic Stroke Nervous System Diseases Stroke Thrombolysis Vascular Diseases

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

The standardized green channel treatment system for acute ischemic stroke includes: Triage nurse triage timely, rapid assessment emergency doctor, suspected stroke the green channel, immediately start in the green channel of stroke accompanied by doctors and nurses stroke patients improve CT examination, intravenous thrombolysis or CT room, emergency room if considering large vascular lesions and the onset time in 6 hours, and rapidly to international for endovascular treatment, if the onset time of more than 6 hours, Rapid evaluation of ischemic penumbra and vascular occlusion by multi-mode imaging. If there are indications for endovascular treatment, go to the cath room for endovascular treatment as soon as possible.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years old;
  • Consistent with the diagnosis of acute ischemic stroke;
  • 24 hours from onset to enrollment;
  • Informed consent

Exclusion criteria

  • Patients who refuse to receive intravenous thrombolysis or intravascular intervention (including intravascular mechanical thrombolysis and arterial thrombolysis);
  • Stroke patients caused by brain tumor, brain trauma and blood diseases;
  • Those with a history of stroke and sequelae affecting the outcome assessment, namely, mRS 2 points before the onset of this stroke;
  • Combined with claudication osteoarthritis rheumatoid arthritis gout arthritis and other limb dysfunction and affect the neurological function examination;
  • Patients with severe hepatic and renal insufficiency (Note: Hepatic insufficiency refers to ALT or AST values greater than 2 times the upper normal limit; Renal insufficiency refers to blood creatinine value greater than 2 times the normal upper limit);
  • Suffering from other serious life-threatening diseases with an expected survival time of less than 3 months;
  • Other diseases that limit neurological function evaluation or affect patient follow-up;
  • A woman planning to be pregnant or breastfeeding;
  • Currently participating in other clinical trials;
  • Refuse to participate in the registration of investigators

Treatment and study plan

Standardized green channel treatment methods for stroke

Other

The measures include six measures: timely triage by triage desk nurses; Rapid evaluation by emergency room physician; If stroke is suspected, the green channel for nosocomial stroke should be activated immediately. Stroke greenway doctors and stroke nurses accompanied patients to complete CT examination; Intravenous thrombolysis in emergency rooms or CT rooms; Suspected macrovascular disease, if the onset time is less than 6 hours, quickly go to the catheter room for intravascular treatment; If the onset time was more than 6 hours, multi-mode imaging was used to quickly evaluate the ischemic penumbra and vascular occlusion, and then the patients were sent to the catheter room for intravascular treatment as soon as possible.

Primary outcomes

  1. Rate of function independent

    Time frame: 90 days after onset

    Rate of modified Rankin Scale(mRS) score less than 3 at 90 days

Secondary outcomes

  1. Rate of mortality

    Time frame: 90 days after onset

    90-day mortality rate

  2. Rate of stroke recurrence

    Time frame: 90 days after onset

    90-day stroke recurrence rate

  3. Rate of cerebral hemorrhage and pneumonia

    Time frame: During hospitalization.

    Incidence of cerebral hemorrhage and pneumonia after thrombolysis or intravascular therapy

Study contacts

Contact information is provided by the study sponsor or research team.

Mingze Chang, Doctor

CONTACT

[email protected]

8615609250698

Sponsors and collaborators

Lead sponsor

Xi'an No.3 Hospital

Other Gov

Registry information

Acronym: Asgctsis

Important dates

Study start
2022
Primary completion
2025
Study completion
2028
First posted
Jun 21, 2022
Registry last updated
Jan 26, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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