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NCT Number: NCT05617846

Application of Antiosteoporosis Therapy in Osteolysis

To report the postoperative complications and limb function of patients with osteolysis after surgery for bone tumors of the extremities who received anti-osteoporosis therapy in Henan Cancer Hospital in the next 10 years.

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Key information

Conditions

Limb; Fusion Complication

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Bone and Soft Tissue ,Henan Cancer Hospital

Zhengzhou, Henan, China

Location contact

Tian Zhichao, Dr.

CONTACT

[email protected]

+8618737187831

About this study

A total of 100 patients with osteolysis after surgery for bone tumors of the four extremities who received anti-osteoporosis treatment in Henan Cancer Hospital in the next 10 years were reported. The basic information, treatment methods, postoperative complications and limb function of these patients were collected.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • No age restriction, male or female.
  • A subtype of bone tumor (including benign, malignant, and metastatic cancer) was confirmed in the pathology department of the research institution.
  • Received excision of bone tumor in research institution.

Exclusion criteria

Not applicable.

Treatment and study plan

Anti-osteoporosis therapy

Other

Bone healing, limb function, and complications of postoperative osteolysis in patients with bone tumors of the extremities treated with anti-osteoporosis therapy.

Primary outcomes

  1. Complications

    Time frame: Collected from the beginning of treatment to 24 months after treatment.

    The incidence of complications after anti-osteoporosis treatment was collected and the severity of complications was evaluated according to CTCAE5.0.

  2. Limb function

    Time frame: Collected from the beginning of treatment to 24 months after treatment.

    Limb function was assessed using the Musculoskeletal Oncology Society (MSTS) scoring scale for seven items, namely movement, pain, stability, deformity, strength, functional activity, and emotional receptiveness. The highest possible score is 35, with 5 points allocated to each project.

Sponsors and collaborators

Lead sponsor

Henan Cancer Hospital

Other Gov

Registry information

Official study title

Efficacy and Safety of Antiosteoporosis Therapy in Patients After Bone Tumor Resection: a Multicenter, Real-world Prospective Cohort Observational Study

Important dates

Study start
2024
Primary completion
2032
Study completion
2032
First posted
Nov 16, 2022
Registry last updated
Jan 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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