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NCT Number: NCT05439330

Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning

The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional, dental-oriented radiographic images for diagnostic purposes.

Recruiting

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Key information

Conditions

TMJ Apical Periodontitis Jaw Diseases MRI Mouth Diseases Periapical Diseases Periapical Periodontitis Periodontal Diseases Periodontal Inflammation Periodontitis Retained Tooth Stomatognathic Diseases Tooth Diseases Tooth, Impacted

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

IOOS

Aarhus, 8000, Denmark

Location status: Recruiting

Location contact

Jennifer Christensen, ph.d.

CONTACT

[email protected]

Rubens Spin Neto, dr.odont

CONTACT

[email protected]

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(one of the following):

  • referred for CBCT imaging of at least one tooth for endodontic reasons
  • referred for intra-oral and/or panoramic imaging covering at least one molar tooth for periodontal reasons
  • referred for CBCT imaging of the TMJ (bilaterally)
  • referred for panoramic imaging of the third molar (retained/semi-retained, uni- or bilateral), prior to treatment planning
  • referred for CBCT imaging prior to implant treatment

Exclusion criteria

  • younger than 18 years
  • unable to give consent
  • pregnant
  • pronounced claustrophobia
  • pacemakers or implanted defibrillators
  • metal shrapnel injuries of the eyes or MRI incompatible metallic inclusions or implants large tatoos
  • non-removable piercings

Treatment and study plan

MRI of teeth and surrounding structures

Device

included above

Primary outcomes

  1. Application of a dental-dedicated MRI in the diagnosis of temporomandibular joint disorders, tissue alterations related to third molars, periapical and periodontal inflammatory diseases, and implant treatment planning

    Time frame: 2½ years

    Diagnosis of pathologies in the TMJ (e.g. disc displacement (anterior/posterior/lateral), inflammation (yes/no), bone changes (yes/no)), periodontal defects (e.g. bone defects (mm), inflammation (yes/no)), periapical pathology (e.g. inflammation (yes/no), apical periodontitis (yes/no)), bone measurements in edentulous areas, and third molars (e.g. relation to surrounding structures (over/same level/under nerve), resorption of neighboring teeth (yes/no)) seen on MRI compared to diagnosis obtained in radiographs. Observations seen on MRI will be compared to observations seen in radiographs.

Study contacts

Contact information is provided by the study sponsor or research team.

Rubens Spin-Neto, ph.D

CONTACT

[email protected]

+4587159713

Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Collaborators

  • Dentsply Sirona Implants and Consumables
  • Siemens Corporation, Corporate Technology

Registry information

Official study title

Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Planning

Important dates

Study start
2022
Primary completion
2026
Study completion
2026
First posted
Jun 30, 2022
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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