Application and Impact Assessment of Ultrasound Super-Resolution Blood Flow Imaging (URM) in Patients With Renal Failure

The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease staging and monitoring treatment response.

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Key information

Conditions

Kidney Failure Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province)

Jinan, Shandong, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

① Clinically diagnosed with acute or chronic renal failure; ② Complete laboratory test results and ultrasound images are available.

Exclusion criteria

① Concurrent severe organ failure; ② Poor image quality; ③ History of renal surgery; ④ Pregnant or breastfeeding women.

Treatment and study plan

Ultrasound super-resolution blood flow imaging

Diagnostic Test

The primary objective is to examine the correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory markers of renal function (eGFR, Scr)

Other names: Patients with acute kidney failure, Patients with chronic kidney failure

Primary outcomes

Correlation between URM parameters (renal cortical and medullary microvascular density, blood flow velocity) and laboratory renal function markers (eGFR, Scr)

Time frame: From enrollment to the end of treatment at 14 days

Sponsors and collaborators

Lead sponsor

Ma Zhe

Other

Registry information

Acronym: URM

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2026
First posted: Mar 20, 2026
Registry last updated: Mar 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed