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Completed

NCT Number: NCT02856139

Appearance of Far Peripheral Retina in Normal Eyes by Ultra-widefield Fluorescein Angiography

PURPOSE: To characterize the appearance of the far peripheral retina of normal eyes using ultra-widefield fluorescein angiography (UWFA).

DESIGN: Prospective observational case series. METHODS: This study enrolled normal eyes with best corrected visual acuity ≥ 20/20, refractive error < 3.00D, and without visible retinal pathologic changes under a slit lamp-based condensing lens. The far peripheral retina was detected by UWFA. Ciliary body thickness (CBT) at 3 mm (CBT1) and 2 mm (CBT2) posterior to the scleral spur was measured by ultrasound biomicroscopy.

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Key information

Conditions

Normal Eyes Peripheral Retina

Age range

Up to 70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, 510060, China

About this study

PURPOSE: To characterize the appearance of the far peripheral retina of normal eyes using ultra-widefield fluorescein angiography (UWFA).

DESIGN: Prospective observational case series. METHODS: This study enrolled normal eyes with best corrected visual acuity ≥ 20/20, refractive error < 3.00D, and without visible retinal pathologic changes under a slit lamp-based condensing lens. Demographic and clinical data such as age, sex, and reasons for undergoing FA were collected. The far peripheral retina was detected by UWFA. The fundal fields obtained using the Heidelberg ultra-widefield lens in a single shot and in montage images were compared with those acquired using the Heidelberg conventional 55° lens. The signs at the peripheral retina detected by UWFA were described and grouped. Ciliary body thickness (CBT) at 3 mm (CBT1) and 2 mm (CBT2) posterior to the scleral spur was measured by ultrasound biomicroscopy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • best corrected visual acuity ≥ 20/20
  • refractive error < 3.00D
  • without visible retinal pathologic changes under a slit lamp-based condensing lens

Exclusion criteria

  • history of ocular surgery
  • presence of ocular or systemic diseases
  • opacity of refractive media, which interfered with the peripheral retina image quality

Treatment and study plan

Primary outcomes

  1. Ultra-widefield fluorescein angiography findings at the far peripheral retina of normal eyes

    Time frame: from November 2014 to January 2016

Secondary outcomes

  1. Ciliary body thickness

    Time frame: from November 2014 to January 2016

Sponsors and collaborators

Lead sponsor

Sun Yat-sen University

Other

Registry information

Official study title

The Director of the Fundus Center of Zhongshan Ophthalmic Center

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Aug 4, 2016
Registry last updated
Aug 4, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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