Aortic Dissection fAlse enlarGement radIomics predictiOn

The objective of this study is to find, in acute phase of aortic dissection, CT scans characteristics through radiomics features, that can help us to predict a significant growth of dissected descending aorta or a false lumen enlargement in order to treat the patient promptly.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Dissection Acute Aortic Syndrome Aneurysm Aortic Diseases Aortic Dissection Cardiovascular Diseases Dissection, Blood Vessel Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Giovanni Tinelli

Roma, Italy

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with previous acute aortic (type A or B) dissection, undergoing medical or surgical therapy and in clinical-radiological follow-up.

Exclusion criteria

Patients with no appropriate radiological follow up;
Patients who died in the acute phase of aortic type A or B dissection.

Treatment and study plan

AORTIC DISSECTION CT SCAN ANALYSIS

Other

Patients with type A or type B acute aortic dissection, treated either with medical therapy or with endovascular/open surgery in the study period and who underwent subsequent radiological follow-up.

Primary outcomes

Predict the false lumen enlargement (>5.5 mm aortic diameter growth at CT follow-up control) through radiomics analysis applied on CT scans.

Time frame: 24 MONTHS

Sponsors and collaborators

Lead sponsor

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Other

Registry information

Acronym: ADAGIO

Important dates

Study start: 2024
Primary completion: 2026
Study completion: 2027
First posted: Aug 12, 2025
Registry last updated: Aug 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting