Antro-pyloro-duodenal Motility in Idiopathic Gastroparesis

Impaired gastric emptying may cause dyspeptic symptoms including nausea, vomiting and even nutritionnal impairment. Delay in gastric emptying may result from antro-pyloro-duodenal motility impairement.

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Key information

Conditions

Gastroparesis Digestive System Diseases Gastrointestinal Diseases Neurologic Manifestations Paralysis Pathological Conditions, Signs and Symptoms Signs and Symptoms Stomach Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Service de Physiologie

Rouen, Haute Normandie, 76000, France

About this study

The aim of this study is therefore to measure antro-pyloro-duodenal motor activity in patients with idiopathic gastroparesis.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Idiopathic gastroparesis or healthy volunteers
Idiopathic gastroparesis must have delayed gastric emptying shown using C13 breath test

Exclusion criteria

Diabetic or post-surgical gastroparesis
Treatment modifying GI motility (prokinetics, opioids...)
Parkinson or neurologic disease
Evoluting inflammatory process or neoplasia
Treatment modifying coagulation
Patients not affiliated to the French healthcare insurance

Treatment and study plan

Primary outcomes

antro-pyloro-duodenal pressure

Time frame: 3h

the main outcome is the pressure measured using pressure sensors within the antrum, the pylorus, and the first part of the duodenum. This will be measured during 3h fast. Pressures measured in the antrum, the pylorus, and the duodenum wiil be compared between healthy volunteers and gastroparetic patients

Sponsors and collaborators

Lead sponsor

University Hospital, Rouen

Other

Registry information

Official study title

Study of the Antro-pyloro-duodenal Motor Dysfunction in Idiopathic Gastroparesis

Important dates

Study start: 2012
Primary completion: 2014
Study completion: 2014
First posted: Jan 26, 2012
Registry last updated: Sep 8, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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