Skip to main content
OpenTrials
Completed

NCT Number: NCT00568217

Antipyretics for Preventing Recurrences of Febrile Seizures

We wanted to find out if the early use of antipyretics is capable in preventing recurrences of febrile seizures. When a child has had his/her first febrile seizure, the parents were instructed to give him/her antipyretic medication every time when the child had a new episode of fever during two years.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Recurrence of Febrile Seizure

Age range

3 month–4 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Heikki Rantala

Oulu, 90014, Finland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • First febrile convulsion

Exclusion criteria

  • Any prior convulsion or antiepileptic medication

Treatment and study plan

Diclofenac, Paracetamol, Ibuprofen

Drug

Immediately if temperature > 38 degree Celsius, diclofenac suppository 1,5 mg/kg once or placebo suppository After eight hours, if temperature still < 38 degree Celsius, acetaminophen mixture 15 mg/kg up to four times a day, or ibuprofen mixture 10 mg/kg up to four times a day, or placebo mixture up to four times a day as long as temperature < 38 degree Celsius

Primary outcomes

  1. recurrence of febrile seizure

    Time frame: two years

Secondary outcomes

  1. we only had the primary outcome measure

    Time frame: two years

Sponsors and collaborators

Lead sponsor

University of Oulu

Other

Registry information

Important dates

Study start
1997
Study completion
2005
First posted
Dec 5, 2007
Registry last updated
Dec 11, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.