Antioxidative Effect of Plantago Asiatica L. Extract

The purpose of this study is to evaluate an acute effect of Plantago asiatica L. extract consumption on antioxidative biomarkers in subjects with mild hyperlipidemia. Subjects will intake Plantago asiatica L. extract with a high fat meal for oxidative stress loading. Antioxidative biomarkers will be measured after single-dose administration of Plantago asiatica L. extract.

Inclusion criteria

• Adults age over 30
• BMI(Body mass index) between 25 and 33 kg/m2
• Total cholesterol between 200mg/dL and 250mg/dL OR Triglyceride between 150mg/dL and 220mg/dL OR LDL-cholesterol between 130mg/dL and 165mg/dL

Exclusion criteria

• Subject who has taken part in other clinical trials within 30 days of screening visit
• Subject who has taken medicines, Chinese medicines and Health/Functional Foods which can affect antioxidative biomarkers within 30days of screening visit
• Subject who is pregnant or breast feeding
• Subject who lost body weight over 4kg within 30days of screening visit
• Alcoholic
• Smoker
• Subject who takes excessive exercise (over 7hours/week)
• Subject who has hypertension(≥140/90mmHg), diabetes(fasting blood glucose ≥126mg/dL), kidney disease, hepatic disease or hyperthyroidism within 2years
• Subject who has an allergy to the ingredients of study product