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Recruiting

NCT Number: NCT07052604

Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients

This study looks at how different antibiotic treatments affect patients in intensive care who have pneumonia caused by the bacteria Stenotrophomonas maltophilia. It compares using one antibiotic versus two antibiotics, and treatment lengths of 7 days versus 14 days, to see which approach helps patients survive better. The study also examines how resistant the bacteria are to antibiotics and how often the pneumonia comes back.

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Key information

Conditions

Pneumonia, Ventilator-Associated Anti-bacterial Agents Cross Infection Disease Attributes Drug Resistance, Bacterial Healthcare-Associated Pneumonia Iatrogenic Disease Infections Intensive Care Units Lung Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Respiratory Tract Diseases Respiratory Tract Infections Stenotrophomonas Maltophilia

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre Hospitalier de Saint-Denis

Saint-Denis, France

Location status: Recruiting

Location contact

Nolan HASSOLD

CONTACT

[email protected]

0142356208

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients (age ≥ 18 years)
  • Hospitalized in Medical Intensive Care Unit between January 1, 2018, and December 31, 2023
  • Intubated and mechanically ventilated
  • Diagnosed with ventilator-associated pneumonia caused by Stenotrophomonas maltophilia

Exclusion criteria

  • Patients under 18 years old
  • Patients who refuse the use of their data for research purposes

Treatment and study plan

Primary outcomes

  1. patient survival based on the antibiotic treatment strategy used (monotherapy vs. combination therapy and 7 vs. 14 days duration).

    Time frame: 28 days

Sponsors and collaborators

Lead sponsor

Centre Hospitalier de Saint-Denis

Other

Registry information

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Jul 4, 2025
Registry last updated
Jul 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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