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Completed

NCT Number: NCT04127682

Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District

Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic resistance. It is important to study physicians' antibiotic prescribing behavior to understand its determinant and for further planning of appropriate interventions to optimize antibiotic prescription.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of medicine- Assiut university

Asyut, 71515, Egypt

About this study

Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic resistance.

In Egypt, a recent study conducted in El-Minya governorate to investigate antibiotic use in PHC centres and in governmental hospitals, revealed that physician prescriptions of antibiotics for ARIs were extremely high as 82% of pediatric visits for ARIs resulted in an antibiotic prescription. Most of these infections are caused by viruses and do not require antibiotic treatment.

Numerous interventions to improve antibiotic prescribing practices have been reported from various countries with varying results. No single intervention appears to have superior efficacy, but combinations of interventions are typically more effective, and strategies that target health care professionals and/or patients (or parents of young children) have achieved success at reducing antibiotic prescriptions for ARIs.

Despite the emergence of antibiotic resistance and international efforts to reduce antibiotic use, prescription still high and inappropriate. Children are a vulnerable group and inappropriate antibiotic prescription may affect their health and may contribute to development of many diseases as allergies beside emergence of antibiotic resistance. Also, most of acute respiratory infections in children are viral infections and they receive antibiotic for it. So,, it is important to study physicians' antibiotic prescribing behavior to understand its determinant and for further planning of appropriate interventions to optimize antibiotic prescription.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Physicians dealing with pediatric cases.
  • GPs, pediatrics, or otolaryngology (ENT) residents.

Exclusion criteria

  • Physician who didn't work at outpatient clinics.
  • Physicians who are specialized and hold a degree.

Treatment and study plan

Antibiotic KAP questionnaire

Other
  • Self-administered questionnaire will be used and containing following Physician information (age, sex, place of work, specialty, years of experience, place of work, and post graduate studies and trainings), Practice information (number of days for outpatient's practice/week, average number of patients /day and average percentage of children with ARIs/day), Antibiotic prescription practice (using of guidelines and causes of prescribing antibiotics in acute URIs), Knowledge about antibiotic resistance and attendance of any conference or educational activities concerned with antibiotic use during the last year, Attitude as regard antibiotic prescription.

Primary outcomes

  1. Physicians knowledge of antibiotic resistance

    Time frame: 6 months

    By self administered questionnaire

  2. Attitude and practice of physicians as regard antibiotic prescription in pediatric cases of acute upper respiratory tract infections.

    Time frame: 6 months

    By self administered questionnaire

Secondary outcomes

  1. Determinants of physicians' antibiotic prescribing behavior in cases of acute upper respiratory tract infection in children.

    Time frame: 6 months

    By self administered questionnaire

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District: An Exploratory Study.

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Oct 15, 2019
Registry last updated
Nov 8, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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