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NCT Number: NCT07117006

Anterior Open Bite Closure by Clear Aligners Versus Fixed Appliances in Adult Patients With Skeletal Open Bite: A Randomized Clinical Trial.

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Brief Summary: Comparative Management of Skeletal Anterior Open Bite Using Mini-Screw Supported Intrusion with Clear Aligners Versus Fixed Appliances

PICO elements

Population: Adults (17-25 years) with uncompensated skeletal anterior open bite.

Intervention: TAD-supported intrusion with clear aligners. Comparison: TAD-supported intrusion with fixed appliances.

Outcomes:

Primary: Anterior open bite closure. Secondary: Molar intrusion, mandibular autorotation, incisor movement and quality of life.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Skeletal Open Bite Clear Aligner Appliance Malocclusion Maxillary Intrusion Mini-screws Open Bite Stomatognathic Diseases Tooth Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of dentistry, cairo university

Cairo, Cairo Governorate, 11528, Egypt

About this study

The aim of the study is to compare the effects of mini-screw supported maxillary posterior segments' intrusion using fixed appliances versus clear aligners.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • uncompensated skeletal openbite with normal incisal show at rest and smiling
  • good oral hygeine

Exclusion criteria

  • systemic disease
  • extraction or missing dentition
  • root resorption in posterior teeth
  • carious or fractured upper posterior teeth peridontal affected upper posterior teeth

Treatment and study plan

miniscrew- supported maxillary posterior segments' intrusion using clear aligners

Device

maxillary posterior segments will be intruded with the aid of miniscrews and clear aligners

Primary outcomes

  1. Anterior open bite closure

    Time frame: 6 months

    the anterior open bite will be measured between the incisors using a digital caliper

Secondary outcomes

  1. amount of maxillary posterior teeth intrusion

    Time frame: 6 months

    the distance between the molar tri-furcation/premolar center to the Frankfurt Horizontal plane

  2. Amount of mandibular posterior teeth extrusion

    Time frame: 6 months

    the distance between molar bi-furcation or premolar center to the mandibular plane

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Anterior Open Bite Closure by Clear Aligners Versus Fixed Appliances in Adult Patients With Skeletal Open Bite: A Randomized Clinical Trial

Acronym: AOB-Mx_INT-MS

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Aug 12, 2025
Registry last updated
Aug 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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