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Completed

NCT Number: NCT06619756

Anomia Treatment Predictors

The goal of this clinical trial is to identify predictors of response to phonological-focused anomia treatment in people with aphasia. The main question it aims to answer is who responds to which type of anomia treatment. Researchers will compare Phonomotor Treatment and Phonological Components Analysis to see which treatment is more beneficial, and for whom. Participants will engage in both treatments over several months.

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Key information

Conditions

Anomia (Word-Finding Impairment) Anomia Aphasia Communication Disorders Language Disorders Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms Speech Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UB Audiology and Speech-Language Pathology Clinic

Buffalo, New York, 14214, United States

About this study

Participants will complete screening and characterization testing to determine eligibility for the study. Each treatment will be administered twice a week, for 10-15 sessions. Pre-treatment and post-treatment testing will also occur for each treatment. There will be a period of no treatment in between the first and second treatment blocks.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Chronic aphasia (6+ months)
  • Anomia
  • Sufficient auditory comprehension to follow task instructions
  • Phonologic impairment

Exclusion criteria

  • Progressive neurological illness or disease, including dementia
  • Chronic medical illness that interferes with adherence to testing schedule
  • Severe, uncorrected vision or hearing impairment that interferes with task completion
  • Moderate-severe apraxia of speech or dysarthria that interferes with task completion

Treatment and study plan

Phonomotor Treatment (PMT)

Behavioral

Anomia treatment focuses on improving word-finding abilities. This intervention targets the phonology of words to improve word-finding.

Phonological Components Analysis (PCA)

Behavioral

Anomia treatment focuses on improving word-finding abilities. This intervention targets the phonology of words to improve word-finding.

Primary outcomes

  1. Naming of Trained Words

    Time frame: Pre-treatment and Immediately post-treatment

    Picture naming of trained words

Secondary outcomes

  1. Naming of Untrained Words

    Time frame: Pre-treatment and Immediately post-treatment

    Picture naming of untrained words

  2. Standardized Assessment of Phonology in Aphasia (SAPA)

    Time frame: Pre-treatment and Immediately post-treatment

    The SAPA assesses phonological processing abilities, including oral reading, rhyme judgments, minimal pair judgments, lexical decision, blending, and parsing.

  3. Philadelphia Naming Test

    Time frame: Pre-treatment and Immediately post-treatment

    The short-form of the Philadelphia Naming Test is a picture naming test of items not seen during treatment.

Sponsors and collaborators

Lead sponsor

State University of New York at Buffalo

Other

Registry information

Official study title

Predictors of Phonological-focused Anomia Treatment

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Oct 1, 2024
Registry last updated
Nov 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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