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OpenTrials
Completed

NCT Number: NCT00498641

Anisometropia Amblyopia Improved by Perceptual Learning and Patching

To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.

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Key information

Age range

3 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

About this study

Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Anisometropia without strabismus
  • An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization
  • All patients wore their spectacle at least one year

Exclusion criteria

  • A history of prior spectacle correction
  • A history of patching or optical penalization
  • The existence of an ocular disease that could contribute to decreased visual acuity
  • Learning difficulties
  • The presence of strabismus

Treatment and study plan

computer program and patching

Procedure

Primary outcomes

  1. Corrected amblyopic logMAR visual acuity and contrast sensitivity function

Sponsors and collaborators

Lead sponsor

Tri-Service General Hospital (TSGH)

Other

Registry information

Important dates

Study start
2005
Study completion
2007
First posted
Jul 10, 2007
Registry last updated
Jul 10, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.