Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation

Wire-guided cannulation of the common bile duct is a standard technique utilized during Endoscopic Retrograde Cholangio-Pancreatography (ERCP) to ensure safe and effective access to the common bile duct via the ampulla of Vater. Due to the anatomy of the ampulla, and the orientation of the biliary orifice, a guidewire with an angled tip may allow easier and safer access to the common bile duct without inadvertent manipulation of the pancreatic duct. The investigators aim to assess the technical and clinical outcomes between an angled-tip guidewire (GW) compared to a straight-tip guidewire in wire-guided cannulation of the common bile duct. The investigators hypothesize that an angled-tip GW is associated with increased rate of successful cannulation, decreased procedure time and decreased rate of post-ERCP pancreatitis in wire-guided biliary cannulation during ERCP.

Inclusion criteria

• patients undergoing ERCP for cholangiography, bile or tissue sampling from the gallbladder or bile duct
• patients undergoing ERCP for treatment of biliary diseases (removal of common bile duct stones, biliary stent placement)

Exclusion criteria

• Patients who are less than 18 years old
• Pregnant patients
• Patients who have undergone previous bile duct cannulation or sphincterotomy
• Patients who have undergone prior endoscopic balloon dilation or needle-knife fistulotomy
• Patients who have undergone gastric surgery (Billroth gastrectomy II, Roux-en-Y gastric bypass)
• Patients with acute pancreatitis
• Patients who refuse endoscopic intervention
• Patients with ampullary tumor, duodenal stenosis, or pre-operatively proven pancreaticobiliary malunion