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Completed

NCT Number: NCT02054767

Anesthetic Efficacy in Irreversible Pulpitis

The purpose of this study was to compare the anesthetic efficacy of articaine, lidocaine and mepivacaine in patients with irreversible pulpitis of mandibular molar.

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Key information

Conditions

Anesthesia

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Emergency Center of the School of Dentistry at the University of São Paulo

São Paulo, 05508-900, Brazil

About this study

Conventional inferior alveolar nerve block (IANB) is the most commonly used technique for achieving pulpal anesthesia in posterior mandibular endodontic procedures. However, IANB has a high failure rate and success rates are even lower when applied for the treatment of mandibular posterior teeth with irreversible pulpitis.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • clinical diagnosis of irreversible pulpitis
  • good health
  • had at least 1 adjacent tooth plus a healthy canine

Exclusion criteria

  • took medication could be interacting with any of the anesthetics used

Treatment and study plan

Intervention: inferior alveolar nerve block injection

Drug

-22 patients received inferior alveolar nerve block injections of 3.6 mL (equivalent to 2 cartridges)

Primary outcomes

  1. pulpal anesthesia

    Time frame: Ten minutes after the inferior alveolar nerve block

    pulpal anesthesia was tested with an electric pulp stimulator

Secondary outcomes

  1. analgesia

    Time frame: the patients were instructed to report any painful sensation at three phases: 1) dentin 2) pulp chamber 3) root canal

    To evaluate the intensity of pain during the pulpectomy a verbal analogic scale was adopted

Other outcomes

  1. lip anesthesia

    Time frame: ten minutes after the inferior alveolar nerve block

    The investigators evaluated the subjective lip anethesia by asking the patient whether his/her lip was numb

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Registry information

Official study title

Anesthetic Efficacy of Articaine, Lidocaine and Mepivacaine in Patients With Irreversible Pulpitis of Mandibular Molar

Important dates

Study start
2010
Primary completion
2012
Study completion
2013
First posted
Feb 4, 2014
Registry last updated
Feb 4, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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