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Completed

NCT Number: NCT03465475

Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

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Key information

Conditions

Safety Issues

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Inonu Univercity

Malatya, 44280, Turkey (Türkiye)

About this study

After the ethical approvel 60 adult patients scheduled for hepatectomy will be taken to study. Patients will be monitored after they are taken to the operating room (ECG, NIBP, SpO2, Body Temp, BIS, NIRS, PVI, PI, ORI). After the anesthesia induction and tarakeal entubation, first twenty patient will take 300 mL fresh gas flow with AGC mode (group 1), Second twenty patient will take 600 mL fresh gas flow with AGC mode (group 2), third twenty patient will take 600 mL fresh gas flow with manually. Hemodynamic and gas consumption data will be recorded. An operating room will be reserved for this study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients undergoing hepatectomy with general anesthesia

Exclusion criteria

  • Essential data missing
  • Patient participating in other research projects
  • Drug allergy
  • Anesthetic complication story

Treatment and study plan

Primary outcomes

  1. Amount of used anesthetic gas (desflurane)

    Time frame: Through study completion, an average of 2 month

    Amount of used desflurane will be determined in milliliter by anesthesia machine (Maquet Flow i40) for each patient.

Secondary outcomes

  1. Heart rate

    Time frame: Through study completion, an average of 2 month

    Heart rate/min

  2. Mean arterial pressure

    Time frame: Through study completion, an average of 2 month

    Mean arterial pressure (mm/Hg)

  3. Peripheral oxygen saturation

    Time frame: Through study completion, an average of 2 month

    Peripheral oxygen saturation (%)

Sponsors and collaborators

Lead sponsor

Inonu University

Other

Registry information

Official study title

Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode With Maquet Flow-i Anaesthesia Machine

Important dates

Study start
2018
Primary completion
2020
Study completion
2021
First posted
Mar 14, 2018
Registry last updated
Aug 25, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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