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OpenTrials
Completed

NCT Number: NCT00691717

Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension

The purpose of this study was to evaluate the safety and intraocular-lowering efficacy of anecortave acetate depot when administered by anterior juxtascleral depot (AJD) for the treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

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Key information

Conditions

Open-angle Glaucoma Eye Diseases Glaucoma Glaucoma, Open-Angle Ocular Hypertension Oular Hypertension

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Charleston

Charleston, South Carolina, 29414, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients 18 years of age or older with open-angle glaucoma (with or without pigment dispersion or pseudoexfoliation) or ocular hypertension.
  • Other protocol-defined inclusion criteria may apply.

Exclusion criteria

  • Patients with any form of glaucoma other than open-angle.
  • Other protocol-defined exclusion criteria may apply.

Treatment and study plan

Anecortave Acetate Sterile Suspension, 30 mg/mL

Drug

Single administration by anterior juxtascleral depot

Anecortave Acetate Sterile Suspension, 60 mg/mL

Drug

Single administration by anterior juxtascleral depot

Anecortave Acetate Sterile Suspension, 75 mg/mL

Drug

Single administration by anterior juxtascleral depot

Anecortave Acetate Vehicle

Other

Single administration by anterior juxtascleral depot

Primary outcomes

  1. Mean Intraocular Pressure at 8 am

    Time frame: Up to 6 months

Secondary outcomes

  1. Percent of Patients Who Remained Rescue Medication-Free at Month 3 (8 am)

    Time frame: Month 3, 8 am

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Official study title

A Study of the Safety and IOP-Lowering Efficacy of Anecortave Acetate in Patients With Open-Angle Glaucoma or Ocular Hypertension

Important dates

Study start
2008
Primary completion
2009
Study completion
2009
First posted
Jun 5, 2008
Registry last updated
Nov 28, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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