Anecortave Acetate in Subfoveal Choroidal Neovascularization (CNV) Due to Wet Age-Related Macular Degeneration (AMD)

The purpose of this study was to evaluate anecortave acetate compared to placebo for maintenance of visual acuity after 24 months of treatment in patients with subfovial choroidal neovascularization (CNV) due to exudative age-related macular degeneration (AMD).

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Key information

Conditions

Macular Degeneration Age-Related Maculopathies Age-Related Maculopathy Eye Diseases Maculopathies, Age-Related Maculopathy, Age-Related Retinal Degeneration Retinal Diseases

Age range

50 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of exudative AMD and a primary or recurrent subfoveal CNV lesion in the study eye.
Other protocol-defined inclusion criteria may apply.

Exclusion criteria

Under 50 years.
Other protocol-defined exclusion criteria may apply.

Treatment and study plan

Anecortave Acetate 15 mg sterile suspension

Drug

0.5 ml of 30 mg/ml administered as a posterior juxtascleral injection

Anecortave Acetate Vehicle

Other

Administered as a posterior juxtascleral injection

Primary outcomes

Mean change from baseline in logMAR visual acuity score at 12 months

Time frame: Month 12

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Official study title

An Evaluation of Safety and Efficacy of Anecortave Acetate Versus Placebo in Patients With Subfoveal Choroidal Neovascularization Due to Exudative Age-Related Macular Degeneration.

Important dates

Study start: 2007
Primary completion: 2008
Study completion: 2008
First posted: Jan 7, 2003
Registry last updated: Nov 28, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed