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OpenTrials
Completed

NCT Number: NCT00315640

Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation

The purpose of this study is to evaluate the safety and efficacy of anecortave acetate depot when administered for the treatment of elevated IOP following treatment with steroids.

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Key information

Conditions

Eye Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

San Paulo, São Paulo, Brazil

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Either gender
  • 18 years of age or older
  • IOP elevation caused by steroid usage
  • Other protocol-defined inclusion criteria may apply

Exclusion criteria

  • Under 18 years of age
  • Other protocol-defined exclusion criteria may apply

Treatment and study plan

Anecortave Acetate Sterile Suspension, 6 mg/mL

Drug

One 0.5 mL anterior juxtascleral depot (AJD) injection in the study eye

Anecortave Acetate Suspension Depot, 30 mg/mL

Drug

One 0.5 mL anterior juxtascleral depot (AJD) injection in the study eye

Anecortave Acetate Sterile Suspension, 60 mg/mL

Drug

One 0.5 mL anterior juxtascleral depot (AJD) injection in the study eye

Anecortave Acetate Vehicle

Other

One 0.5 mL anterior juxtascleral depot (AJD) injection in the study eye

Primary outcomes

  1. Mean change in IOP at Week 4 from Baseline

    Time frame: Week 4

Sponsors and collaborators

Lead sponsor

Alcon Research

Industry

Registry information

Official study title

A Study of the Safety and Efficacy of Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation

Important dates

Study start
2005
Primary completion
2009
Study completion
2009
First posted
Apr 19, 2006
Registry last updated
Nov 28, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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