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OpenTrials
Completed

NCT Number: NCT03864380

Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort

The cardiovascular parameters of prolonged physical exercice have been studied, but very little data is available about the retinal vascularization.

The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition.

The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise.

This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date.

The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized.

the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.

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Key information

Conditions

Retinal Vascular Disorder Sport Injury

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Fondation A de Rothschild

Paris, 75019, France

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Person registered at the 2019 Paris Marathon

Exclusion criteria

  • Ophthalmological disorders making access to the fundus impossible for both eyes

Treatment and study plan

Color retinography

Diagnostic Test

Non mydriatic color retinography within 1 month before and within 1 hour after the marathon

OCT-A

Diagnostic Test

Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon

Blood pressure measurement

Diagnostic Test

Blood pressure measurement within 1 month before and within 1 hour after the marathon

Primary outcomes

  1. Density of retinal vascular plexuses

    Time frame: up to 1 hour

    Percentage, Measurement with OCT-A

Sponsors and collaborators

Lead sponsor

Fondation Ophtalmologique Adolphe de Rothschild

Network

Registry information

Acronym: MARETINE

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Mar 6, 2019
Registry last updated
May 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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