Analysis of the Persistence, Reservoir and HIV Latency

The APRIL study aims at analyzing HIV reservoirs, latency and persistence on antiretroviral therapy. It enrolls HIV-infected adults providing blood samples of which peripheral blood mononuclear cells are stored. The frequency, phenotype and inducibility of HIV-infected cells are then analyzed. These parameters may vary across the different clinical and therapeutic settings.

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Key information

Conditions

HIV Infected Individuals Informed Consent

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

HIV-infection
Adults (>18 years)
Social insurance
Informed consent

Exclusion criteria

HIV-uninfected
<18 years
Lack of social insurance
Lack or withdraw of consent

Treatment and study plan

Primary outcomes

HIV-Flow

Time frame: 1 day

Study contacts

Contact information is provided by the study sponsor or research team.

Pierre GANTNER, MCU-PH

CONTACT

[email protected]

03 69 55 16 32

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Official study title

APRIL Study: Analysis of the Persistence, Reservoir and HIV Latency

Acronym: APRIL

Important dates

Study start: 2023
Primary completion: 2027
Study completion: 2027
First posted: Mar 2, 2023
Registry last updated: Mar 2, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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