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NCT Number: NCT04754906

Analysis of Motor Skills in Subjects Aged 55 and Over: the Role of Cognitive Abilities for Planning Movement.

Falling is an event that is more frequent and severe in older age. It can lead to a loss of autonomy and a decrease in quality of life. It is therefore important to understand this phenomenon in order to better prevent it. Among the multiple risk factors associated with falling, recent research has shown a link between the decline in cognitive abilities (i.e., the mental processes that form our knowledge, such as memory) and the risk of falling. However, the impact of this cognitive decline on motor skills is still poorly understood. The purpose of this research is to study how the changes induced by aging affect motor skills. This would make it possible to take a new look at the phenomenon of falls occurring in the elderly and, in the long term, to improve the prevention and rehabilitation.

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Key information

Conditions

Mild Cognitive Disorder Mental Disorders Neurocognitive Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Chu Dijon Bourgogne

Dijon, 21000, France

Location status: Recruiting

Location contact

Patrick MANCKOUNDIA

CONTACT

[email protected]

0380293970

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Neurotypical subjects group:
  • Person aged 18 to 40 years
  • Person who has given oral consent
  • Affiliated to national health insurance
  • Right-handed person
  • Group of elderly neurotypical subjects:
  • Person over 55 years of age
  • Person who has given oral consent
  • Affiliated to national health insurance
  • No cognitive problems (MMSE score >26)
  • Right-handed person
  • Elderly mild cognitive disorder subject group:
  • Person over 55 years of age
  • Person who has given oral consent
  • Diagnosis of Mild Cognitive Disorder made by a neurologist at the Centre Mémoire Ressources et Recherche (CMRR) of the University Hospital of Dijon, following the recommendations of the National Institute for Aging and Alzheimer's Association (Albert et al., 2011) This diagnosis is based on psychometric tests, brain imaging and the evolution of cognitive disorders, including an MMSE test.
  • Right-handed person

Exclusion criteria

  • Neurological or psychiatric history with the exception of the TCL group.
  • Follow-up of drug treatment in the last three months that may affect cognitive and/or motor skills.
  • Received a shoulder prosthesis on the dominant side.
  • Received a hip and/or knee replacement less than a year ago.
  • Disabling joint disease of the hip or knee shoulder
  • Protected adults (curatorship, guardianship)
  • Person deprived of their liberty b judicial or administrative decision
  • Pregnant, parturient or breastfeeding woman
  • Major unable to consent

Treatment and study plan

Sequence 1

Other

perform arm movements towards a target

Sequence 2

Other

judge the verticality of an object

Sequence 3

Other

In standing position, point as quickly as possible with the right arm at the diode that will light up in front of the participant.

Primary outcomes

  1. Sequence 1: symmetry ratio of the finger speed profile

    Time frame: through study completion, an average of 3 years

  2. Sequence 2 : perception bias (error in degrees of angle) of dynamic subjective visual vericality

    Time frame: through study completion, an average of 3 years

  3. Sequence 3 : activation time of the focal muscles in relation to the postural muscles

    Time frame: through study completion, an average of 3 years

Study contacts

Contact information is provided by the study sponsor or research team.

Patrick MANCKOUNDIA

CONTACT

[email protected]

0380293970 ext. +33

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire Dijon

Other

Registry information

Acronym: Vieillissement

Important dates

Study start
2021
Primary completion
2028
Study completion
2028
First posted
Feb 15, 2021
Registry last updated
Sep 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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