Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in Characterization of Gingival Systemic Health, Gingivitis and Periodontitis

The aim of the study is to identify tissue changes among healthy patients, patients with gingivitis and with periodontitis before and after treatment, by analyzing tissues changes through Line-Field Confocal Optical Coherence Tomography (LC-OCT)

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Key information

Conditions

Gingival Diseases Gingivitis Infections Mouth Diseases Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Policlinico G. Rodolico

Catania, Italy, 95100

About this study

The tissue changes among healthy patients, patients with gingivitis and with periodontitis before and after treatment, by analyzing tissues changes through Line-Field Confocal Optical Coherence Tomography (LC-OCT) will be evaluated through changes on epithelium before and after non surgical periodontal treatment

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of gingivitis or periodontitis by the presence of elevated bleeding or probing index or probing pocket depth

Exclusion criteria

Smoking
Any systemic diseases that could influence the gingival structure

Treatment and study plan

Line-Field Confocal Optical Coherence Tomography (LC-OCT)

Device

Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in separate groups of patients with gingivitis, periodontitis and healthy patients

Other names: Line-Field Confocal Optical Coherence Tomography (LC-OCT) in all patients

Primary outcomes

Visual epithelial surface change

Time frame: 6-months

Analysis of disruption of superficial epithelium and basal line

Sponsors and collaborators

Lead sponsor

University of Catania

Other

Registry information

Official study title

Analysis of Line-Field Confocal Optical Coherence Tomography (LC-OCT) in the Characterization of Gingival Systemic Health, Gingivitis and Periodontitis and Effects of Periodontal Treatment

Acronym: Perio-LC-OCT

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Feb 18, 2025
Registry last updated: Feb 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed