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NCT Number: NCT06918860

Analysis of Intramedullary Nail and Prosthetic Reconstruction After Surgical Treatment of Bone Metastases of Proximal Femur

The investigators will collect data of patients treated surgically for impending or pathological fracture of the proximal femur due to bone metastases between 01/01/2000 and 31/12/2023 with IMN or THA or HHA or MegaTHA or Mega.

After pre-screening the databases of the respective sites, the investigators expect to find approximately a total of 600 patients. A review will be made from the medical records, radiological imaging, and histological data of partecipants.

Recruiting

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Key information

Conditions

Bone Metastases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Irccs Istituto Ortopedico Rizzoli

Bologna, Emilia-Romagna, 40134, Italy

Location status: Recruiting

Location contact

Costantino Errani, MD

CONTACT

[email protected]

0516366 ext. Ext. 103

Roberta Laranga, PhD

CONTACT

[email protected]

0616366 ext. 5123

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male and female adult patients surgically treated between 01/01/2000 and 31/12/2023 in Rizzoli Orthopaedic Institute and in Massachusetts General Hospital.
  • Age ≥18 y (at the time of surgery)
  • Patients with impending or pathological fracture due to bone metastases of the proximal femur (head/neck, intertrochanteric, subtrochanteric area).
  • Patients who underwent either IMN or THA or HHA or Mega or MegaTHA.
  • Patients with available clinical and imaging data.

Exclusion criteria

  • Patients with pathological or impending fracture of proximal femur due to primary bone tumor.

Treatment and study plan

Analysis

Other

Analysis and review of imaging and clinical data

Primary outcomes

  1. Analysis of implant survival

    Time frame: through study completion, an average of 1 year

    Assess the longevity associated with the different surgical treatments used for proximal femur bone metastases.

  2. Analysis of complications

    Time frame: At baseline ( T0)

    Assess the post-operative complications associated with the different surgical treatments used for proximal femur bone metastases.

  3. Analysis of functional score

    Time frame: 1 year

    Assess the functional score associated with the different surgical treatments used for proximal femur bone metastases.

Study contacts

Contact information is provided by the study sponsor or research team.

Costantino Errani, MD

CONTACT

[email protected]

0516366 ext. Ext. 103

Roberta Laranga, PhD

CONTACT

[email protected]

0516366 ext. Ext. 5123

Sponsors and collaborators

Lead sponsor

Costantino Errani

Other

Registry information

Official study title

Complications, Implant Survival and Functional Results After Surgical Treatment of Bone Metastases of Proximal Femur With Intramedullary Nail or Prosthetic Reconstruction

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Apr 9, 2025
Registry last updated
May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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