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NCT Number: NCT06365138

Analysis of Individual Activity at the Time of Aortic Rupture in Patients With Abdominal Aortic Aneurysms

It is currently unclear what activities aneurysms are involved in at the time of rupture. The aim of the study is to determine the activity performed at the time of aneurysm rupture.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

The scientifically proven risk factors that significantly favor the rupture of an aortic aneurysm are female gender, the maximum diameter of the aortic aneurysm and the patient's current smoking status.

However, no analysis of the occupation performed at the time of aortic rupture of an abdominal aortic aneurysm has yet been carried out.

High arterial systolic blood pressure can promote aortic rupture. Blood pressure peaks can occur during physical exertion, for example when lifting heavy loads or during defecation.

Patients with an existing intact aortic aneurysm are currently advised to avoid such behaviors as a preventive measure. This includes, among other things, the practice of strength training or certain types of sport. This can subsequently lead to a reduction in quality of life, although this cannot currently be substantiated by scientific data. There is also no current guideline recommendation in this regard.

Furthermore, the role of stress and / or emotionally stressful events in connection with the occurrence of aortic ruptures has not yet been recorded in the literature. There is work on this in connection with aortic dissections, which postulates that an increase in emotional or psychological stress can lead to acute hypertension, which can cause a previously damaged aorta to rupture. A similar pathomechanism would also be conceivable for the rupture of aortic aneurysms.

There are indications that, in addition to gender-specific differences in the occurrence of aortic ruptures, there is also a different risk of rupture based on certain pre-existing conditions, dietary habits and age.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • inclusion of all patients with ruptured aortic aneurysm in Augsburg University Hospital
  • Written consent to participate in the study by the patient or their legal representative

Exclusion criteria

  • Lack of consent

Treatment and study plan

Bahaviour at the time of an aortic aneurysm rupture

Behavioral

Questionnaire and patient interview, diary for day of rupture and the three previous days

Primary outcomes

  1. Occupation at the time of the aortic aneurysm rupture

    Time frame: Occupation at the day of the aortic rupture and the three days prior

    Occupation at the time of the aortic aneurysm rupture

Study contacts

Contact information is provided by the study sponsor or research team.

Tobias Warm, MD

CONTACT

[email protected]

+49821400161068

Yvonne Gosslau, MD

CONTACT

[email protected]

+49821400161977

Sponsors and collaborators

Lead sponsor

University Hospital Augsburg

Other

Collaborators

  • Epidemiology, Medical Faculty, University Augsburg

Registry information

Important dates

Study start
2024
Primary completion
2029
Study completion
2030
First posted
Apr 15, 2024
Registry last updated
Apr 15, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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