Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)

This study looks at patients who were treated for cerebral toxoplasmosis at CHSD between 2004 and 2024. It focuses on analyzing their cerebrospinal fluid (CSF) to better understand the biological signs of the disease. The goal is to see if CSF results can show signs of meningitis, even though it's not commonly reported, and to describe any co-infections, symptoms, brain imaging findings, and patient outcomes.

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Key information

Conditions

Toxoplasmosis, Cerebral Abscess Blood-Borne Infections Brain Abscess Brain Diseases Central Nervous System Diseases Central Nervous System Infections Central Nervous System Parasitic Infections Central Nervous System Protozoal Infections Cerebrospinal Fluid Coccidiosis Communicable Diseases Genital Diseases HIV Infections Immune System Diseases Immunologic Deficiency Syndromes Infections Lentivirus Infections Meningitis Nervous System Diseases Neuroinflammatory Diseases Parasitic Diseases Protozoan Infections RNA Virus Infections Retroviridae Infections Sexually Transmitted Diseases Sexually Transmitted Diseases, Viral Suppuration Toxoplasmosis Urogenital Diseases Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

France

Saint-Denis, France

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patients (age 18 years) hospitalized at CHSD between January 1, 2004 and March 31, 2024 for cerebral toxoplasmosis

Exclusion criteria

Under 18 years ols

Treatment and study plan

Primary outcomes

Number of participants with treatment-related adverse events as assessed by CTCAE v4.0

Time frame: From hospital admission to completion of diagnostic lumbar puncture and initial treatment (typically within the first 7 days of hospitalization).

Sponsors and collaborators

Lead sponsor

Centre Hospitalier de Saint-Denis

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Jun 29, 2025
Registry last updated: Jun 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed