Analysis of Biological Progression and Regression of HELLP Syndrome in Time

Prospective observational study about progression and regression of biological parameters of HELLP syndrome

Completed

Looking for future studies?

Key information

Conditions

HELLP Syndrome Blood Platelet Disorders Cytopenia Death Female Urogenital Diseases and Pregnancy Complications Hematologic Diseases Hemic and Lymphatic Diseases Hypertension, Pregnancy-Induced Maternal Death Parental Death Pathologic Processes Pathological Conditions, Signs and Symptoms Pre-Eclampsia Preeclampsia Pregnancy Complications Thrombocytopenia Urogenital Diseases

Sex eligibility

Female

Study type

Observational

Primary location

CHU Mohammed VI of Marrakech

Marrakesh, Marrakesh-Safi, 40000, Morocco

About this study

Data collection included a comprehensive review of pathological histories, identification of complications based on clinical presentation, daily monitoring of biological parameters, documentation of transfusion events, recording of corticosteroid administration according to gestational age, and detailed reporting of extraction and analgesia techniques.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Pregnant women who are admitted to the maternal ICU for a biological HELLP syndrome

Exclusion criteria

Patients whose biological presentation was attributable to other conditions, such as microangiopathies or leukemia.
Patients who benefited from plasma exchange therapy

Treatment and study plan

Primary outcomes

Platelets count

Time frame: Up to 10 days

Platelets count will be monitored daily before and after delivery

Secondary outcomes

Concentration of Lactate dehydrogenase

Time frame: Up to 10 days

Monitored daily before and after delivery
Concentration of Liver enzymes

Time frame: Up to 10 days

daily monitoring of alkaline phosphatase, alanine transaminase before and after delivery

Sponsors and collaborators

Lead sponsor

CHU Mohammed VI Marrakech

Other

Registry information

Official study title

Biological Evolution of HELLP Syndrome

Important dates

Study start: 2023
Primary completion: 2025
Study completion: 2025
First posted: Jan 6, 2025
Registry last updated: Mar 31, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting