Analgesic Territory Assessment of the Spinal Erector Block Using Pupillometry

Few works have studied the area of analgesia covered by the spinal erector block in an objective manner, especially on the cephalo-caudal spread. The available data are dissection works or subjective data such as thermoalgesic or epicritic sensitivity.

This information would however be relevant in order to propose a better analgesia. Indeed, it could explain certain failures by insufficient diffusion of the block. The use of a multistage block could be relevant, especially in the case of osteosynthesis on several vertebral levels.

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Key information

Conditions

Anesthesia, Local

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Saint-Etienne

Saint-Etienne, France

About this study

Pupillometry makes possible to monitor analgesia based on the pupillary dilation reflex to pain. The goal is to establish an objective mapping of these type of analgesia from these data.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients receiving erector spinae block for pain management of spinal osteosynthesis

Exclusion criteria

Patient refusal
Known allergy to local anesthetics
Contraindication to locoregional anesthesia (haemostasis disorder, infection, peripheral neuropathy)
Technical impossibility to perform a spinal erector block
Pathology with dysautonomia altering the pupillary reflex: diabetes mellitus with diabetic retinopathy, multiple sclerosis, systemic amyloidosis, uncontrolled hypertension, glaucoma
Current treatment likely to alter pupillary dilation reflex to pain : antiemetic (droperidol, metoclopramide), alpha-2 agonist (clonidine)
Serious psychiatric history
Drug abuse
Pregnancy

Treatment and study plan

Data collected

Other

data collected:

Morphological data of the patients
Data of the erector block realization
Pupillometric data :the variation of the pupil size on stimulation (in percentage of the base diameter)

Primary outcomes

variation of the pupil size (in percentage)

Time frame: During the surgery

Evaluation the territory covered by the spinal erector block by variation of the pupil size (in percentage).

Variation of the pupil size on stimulation will allow to deduce if the dermatome is covered by the spinal erector block analgesia.

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne

Other

Registry information

Acronym: TEASER

Important dates

Study start: 2023
Primary completion: 2024
Study completion: 2024
First posted: Mar 9, 2023
Registry last updated: May 21, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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