Skip to main content
OpenTrials
Completed

NCT Number: NCT05097937

Analgesic Mechanisms of Percutaneous Electrolysis

Percutaneous electrolysis is based on the application of a galvanic current through an acupuncture needle. The underlying mechanisms that explain the efficacy of this technique are not completely well understood. The objective is to delve into the neurophysiological analgesic effects of percutaneous electrolysis. Participants will be assigned to one of three intervention groups. The analgesic effects of the technique will be evaluated by means of variables related to endogenous pain modulation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Percutaneous Electrolysis Agnosia Analgesia Endogenous Analgesia System Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pain Modulation Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Facultad de Enfermería y Fisioterapia de la Universidad de Salamanca

Salamanca, 37007, Spain

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Asymptomatic subjects
  • Signature of the informed consent

Exclusion criteria

  • Fear of needles
  • Any pathology or process that causes pain
  • Neurological, rheumatologic, cardiovascular or metabolic diseases
  • Cutaneous alterations and cognitive or sensitivity disorders
  • Pregnancy
  • Recent intake of alcohol or caffeine
  • Vigorous physical activity on the day of testing

Treatment and study plan

Sham intervention

Other

The needle will be inserted into the right common extensor tendon of the epicondyle for 90 seconds without galvanic current.

Low intensity percutaneous electrolysis

Other

A single impact of galvanic current will be applied in the common extensor tendon of the epicondyle (right side) with an intensity of 0.3 mA for 90 seconds.

High intensity percutaneous electrolysis

Other

Three impacts of galvanic current will be applied in the common extensor tendon of the epicondyle (right side) with an intensity of 3 mA and a duration of 3 seconds each.

Primary outcomes

  1. Changes from baseline in Pressure Pain Thresholds (PPT)

    Time frame: Baseline and immediately after the intervention

    PPTs will be measure by algometry in the common extensor tendon of the epicondyle, bicipital groove and tibialis anterior muscle (all of the right side).

Secondary outcomes

  1. Changes from baseline in Conditioned Pain Modulation (CPM)

    Time frame: Baseline and immediately after the intervention

    CPM will be assess by upper extremity submaximal effort tourniquet test with algometric measures in the common extensor tendon of the epicondyle, bicipital groove and tibialis anterior muscle (all of the right side).

  2. Changes from baseline in Temporal Summation (TS)

    Time frame: Baseline and immediately after the intervention

    Assessed by Verbal Numeric Rating Scale (11-point). 10 consecutive pressures will be applied in the three previous locations (epicondyle, bicipital groove and tibialis anterior) with the algometer at the intensity of the pressure pain threshold

Sponsors and collaborators

Lead sponsor

University of Salamanca

Other

Registry information

Official study title

Neurophysiological Effects of Percutaneous Electrolysis Related to Endogenous Pain Modulation

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Oct 28, 2021
Registry last updated
Feb 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.