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NCT Number: NCT06088420

Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section

comparing analgesic efficacy of different nerve blocks on post operative cesarean sections.

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Key information

Conditions

Post Operative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Mahmoud Mamdouh Ekram

Asyut, Manfalout, Egypt

Location status: Recruiting

Location contact

Ghada Abo Elfadl, prof

CONTACT

[email protected]

01005802086

About this study

Analgesic efficacy of Erector Spinae, Quadratus Lumborum and Intrathecal Morphine for post operative pain relief after cesarean section,

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-40 years old
  • more or equal 37 weeks of gestation
  • ASA 1,2
  • Elective cesarean delivery

Exclusion criteria

  • Patient refusal
  • inability to cooperate with or understand the study
  • local infection.
  • bleeding disorder
  • known anaphylaxis to any drug used in the trial
  • ASA physical status more than 2
  • emergency operations
  • chronic opioid use (opioid use in the past 3 months)
  • Neurologic deficit or disorder
  • contraindication to regional anesthesia.

Treatment and study plan

Intrathcal Morphine Group

Procedure

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs(10-12 mg 0.5% hyperbaric bupivacaine)

Quadratus Lumborum nerve block(QL) group

Procedure

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral QL block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Erector Spinae nerve block (ESP)group

Procedure

intrathecal morphine (150 μg) in addition to standard spinal anesthetic drugs (10-12 mg 0.5% hyperbaric bupivacaine) + bilateral ESP block by injecting 20 ml of 0.25% isobaric bupivacaine bolus with 4 mg ) dexamethasone as an adjuvant

Primary outcomes

  1. Duration of analgesia until first analgesic request.

    Time frame: 24 hours .

    the time interval from immediate postoperative period until NRS reached 4

Study contacts

Contact information is provided by the study sponsor or research team.

Ghada Abo Elfadl

CONTACT

[email protected]

01005802086

Ghada Abo Elfadl, MD

CONTACT

[email protected]

01005802086

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Analgesic Efficacy of Erector Spinae Block , Quadratus Lumborum Block, and Intrathecal Morphine for Postoperative Pain Relief After Cesarean Section: A Randomized Study

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Oct 18, 2023
Registry last updated
Apr 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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