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Completed

NCT Number: NCT05094323

Analgesia After Video-Assisted Thoracic Surgery

Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).

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Key information

Conditions

Post Operative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Seham M. Moeen

Asyut, 71111, Egypt

About this study

Although less invasive, postoperative analgesia remains challenging in patients undergoing uniportal video-assisted thoracic surgery (VATS).

Adequate postoperative pain relief is imperative to hasten functional recovery, accelerate discharge from the hospital, and reduce chronic postsurgical pain.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients scheduled for uniportal VATS under general anesthesia, ASA status I-III, aged from 18 to 70 years old of both sex.

Exclusion criteria

  • Contraindications to regional block
  • Pregnancy
  • Body mass index (BMI) > 30 Kg/m2
  • Psychiatric diseases
  • Severe renal, liver, or cardiac dysfunction

Treatment and study plan

Ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine

Drug

Patients will receive ultrasound-guided deep serratus anterior plane block with isobaric bupivacaine.

Local wound infiltration with isobaric bupivacaine

Drug

Patients will receive local wound infiltration with isobaric bupivacaine.

Ultrasound-guided thoracic paravertebral block with isobaric bupivacaine

Drug

Patients will receive ultrasound-guided thoracic paravertebral block with isobaric bupivacaine.

Primary outcomes

  1. Time to first analgesic requirement

    Time frame: 24 hours after surgery

    Assessed in minutes

Secondary outcomes

  1. Postoperative pain intensity

    Time frame: 24 hours after surgery

    Assessed by the numerical rating pain scale, an 11-point scale graded from 0 to 10 (0 = no pain, 10 = the worst imaginable pain)

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Analgesic Efficacy of Ultrasound-Guided Deep Serratus Anterior Plane Block, Local Wound Infiltration, and Thoracic Paravertebral Block After Uniportal Video-Assisted Thoracic Surgery: A Randomized Trial

Important dates

Study start
2022
Primary completion
2025
Study completion
2025
First posted
Oct 26, 2021
Registry last updated
Jan 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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