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OpenTrials
Completed

NCT Number: NCT04069403

An Opioid Prescribing Nudge

Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures.

Test the impact of reports on opioid prescriber behaviors with the following primary measures: number of prescriptions with concurrent benzo within reporting period, number of prescriptions with concurrent muscle relaxants within reporting period, and number of encounters with naloxone prescriptions for patients with any opioid-related diagnosis within reporting period.

Create a blueprint to implement the concurrent opioid prescribing nudge intervention in other settings.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Duke University Medical Center

Durham, North Carolina, 27705, United States

About this study

The Concurrent Opioid Prescribing Nudge project intends to address multiple points within the opioid-use cycle through the development of standardized and scalable reporting mechanisms to provide social comparisons and feedback to physicians across the Duke Health System regarding their concurrent and co- opioid, benzodiazepines, and muscle relaxant prescribing practices. Concurrent are hereby defined as:

  • writing a new opioid prescription for a patient with a benzodiazepine prescription within the last 3 months,
  • writing a new benzodiazepine prescription for a patient with a opioid prescription within the last 3 months,
  • writing a new muscle relaxant prescription for a patient with an opioid prescription within the last 3 months,
  • writing a new opioid prescription for a patient with muscle relaxant prescription within the last 3 months, or
  • writing a new prescription for both an opioid and benzodiazepine or opioid and muscle relaxant.

The proposed project will leverage insights from behavioral economics to design informational and social incentives to reduce concurrent practices and mitigate opioid harm. Opioid prescribers (attending physicians, residents, and advanced practice providers) at participating departments and clinics in the Duke Health System will be randomized to a control or intervention arm. Over six month reporting periods beginning fall 2019, providers in the intervention arms will receive monthly reports with their individual prescribing patterns and comparison to peer prescribing patterns for the following measures: number of prescriptions with concurrent opioid active prescriptions of opioid/ benzodiazepines, number of prescriptions with concurrent opioid active prescriptions of opioid/muscle relaxants, and number of missed opportunities to prescribe naloxone to patients with any opioid-related diagnosis. The control arm will receive usual clinical education and feedback. Interventions will be implemented at participating departments and clinics utilizing a stepped-wedge timeline.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The primary population of focus for this study is:

  • attending physicians
  • residents
  • advanced practice providers

hereby referred to as opioid prescribers in Duke University Health System and may include these departments and clinics:

  • Emergency Department
  • Neurology, Pain Management
  • Primary Care
  • Psychiatry, Sleep Disorder Clinic
  • Spine

All opioid prescribers in these settings will be identified in partnership with Duke University Health System.

Exclusion criteria

  • Providers not identified above

Treatment and study plan

Automated Reports on prescription patterns for their patients

Other

de-identified aggregate reports

Other names: de-identified reports, prescribers' prescribing patterns

Primary outcomes

  1. Change in Opioid prescribing habits

    Time frame: Baseline, 6 Months

    Using baseline concurrent opioid prescribing metrics obtained (at the individual prescriber level) during their initial month and month prior in the Duke Health System, measure changes in Opioid n prescription orders as measured by provider prescriptions

  2. number of prescriptions with concurrent benzo within reporting period

    Time frame: 6 Months

    Identify the number of prescriptions with concurrent benzo over 6 months

  3. number of prescriptions with concurrent muscle relaxants within reporting period

    Time frame: 6 Months

    Identify the number of prescriptions with concurrent muscle relaxants over 6 months

  4. number of encounters with naloxone prescriptions for patients with any opioid-related diagnosis within reporting period

    Time frame: 6 Months

    Identify the number of encounters with naloxone prescriptions for patients with any opioid-related diagnosis over 6 months

Sponsors and collaborators

Lead sponsor

Duke University

Other

Registry information

Official study title

An Opioid Prescribing Nudge: Leveraging Behavioral Economics to Reduce Opioid Harms Within Health Systems

Acronym: OHS

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Aug 28, 2019
Registry last updated
Jun 30, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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