An Open-label Pharmacokinetic Study of TS-172 in Patients on Hemodialysis

Inclusion criteria

• Japanese male patients (outpatients) with chronic kidney disease receiving hemodialysis (HD or HDF) 3 times a week for at least 12 weeks prior to the screening test
• Patients aged >= 18 and < 75 years at the time of obtaining informed consent

Exclusion criteria

• Patients with gastric or intestinal ulceration or a history of them within the past year prior to the date of initiation of treatment, or patients with inflammatory bowel disease or irritable bowel syndrome, or a history of these within the past 5 years prior to the date of initiation of treatment
• Patients scheduled for renal transplantation, home hemodialysis or change of dialysis facility (transfer or temporary dialysis at other hospital) during the study period
• Patients who frequently experience diarrhea (defined as Bristol Stool Scale score of 6 or higher)