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OpenTrials
Active, Not Recruiting

NCT Number: NCT07152470

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.

The goal of this clinical trial is to learn if motus, a natural supplement can support healthy weight loss and fat loss in a real world setting without caloric restrictions or exercise requirements.

The main questions it aims to answer are:

Can a daily dose of motus result in statistically significant weight loss over 3 month and 6 month time points.

Participants will:

Weigh-in at baseline and every week thereafter Take drug motus every day Complete a food tracker app for every meal and drink product consumed daily Complete an exercise tracker for any activities performed daily Complete weekly satisfaction surveys on various topics

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Overweight and Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tonum Health

West Palm Beach, Florida, 33401, United States

About this study

A prospective, observational human study was conducted with 100 participants (ages 25-68, BMI ≥25) over an initial 12-week period, followed by a 12-week extension phase for 40 continuing participants. All subjects received motus (4-capsule daily dose) and were instructed to track food intake and exercise via food tracker app and digital fat measurement scales. No caloric restriction was mandated, and participants could optionally receive nutritional counseling. Weekly weigh-ins and quality of life surveys were completed. No financial compensation was provided. Participants were stratified post hoc into three behavioral groups based on food and activity logs reviewed by registered dietitians: Category 1 (healthy diet + exercise 4+ times per week), Category 2 (average diet + exercise 2-3 times per week), Category 3 (average diet + no exercise) and Category 4 (poor diet + no exercise).

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI >25
  • Willing to complete daily diary and weekly weigh-ins
  • Willing to take motus daily

Exclusion criteria

  • BMI<25
  • Unwilling to complete daily diary and weekly weigh-ins
  • Currently taking a prescribed weight loss medication
  • Currently or planning to be pregnant

Treatment and study plan

Diet and Exercise Tracking

Behavioral

To determine if diet and/or exercise had any impact on weight loss while taking motus.

Primary outcomes

  1. Total Weight Loss

    Time frame: 26 weeks

    Total weight loss as a percentage of total body weight

  2. Body Fat Loss

    Time frame: 26 weeks

    Total body fat loss compared to lean mass loss

Sponsors and collaborators

Lead sponsor

Prostasis, LLC, dba Tonum Health

Industry

Registry information

Official study title

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss in a Real World Setting.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Sep 3, 2025
Registry last updated
Sep 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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