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NCT Number: NCT06262464

An OCD Prevention Programme for at Risk Adults

The main purpose of this randomised clinical trial is to test the efficacy of a prevention program for adult who are at risk of developing OCD, thus constituting a form of tertiary prevention.

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Key information

Conditions

Obsessive-Compulsive Disorder Anxiety Disorders Mental Disorders

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Babes-Bolyai University, Faculty of Psychology and Educational Sciences, Department of Clinical Psychology and Psychotherapy

Cluj-Napoca, Romania, 400015

Location status: Recruiting

Location contact

Roxana AI Cardos, PhD Student

CONTACT

[email protected]

0040751477323

About this study

After being informed about the study and giving written informed consent, all eligible participants will be randomised into the experimental group or the control group (TAU). Participants will be blind to the group allocation.

The experimental group will undergo a two weeks OCD prevention program, consisting of three group sessions per week.

The control group will not receive any intervention.

Researchers will compare the experimental group to the control group to test wether the prevention programme is efficient in reducing OCD symptomatology.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age over 18

Exclusion criteria

  • clinically diagnosed OCD
  • current psychiatric/psychotherapeutic treatment
  • personality disorder diagnosis
  • suicidal ideation

Treatment and study plan

Prevention

Behavioral

A cognitive-behavioural prevention programme.

Primary outcomes

  1. Change from baseline in OCD symptoms on the OCI-R after the intervention

    Time frame: Baseline and Week 2

    The OCI-R is a validated self-report instrument assessing OCD symptoms. Possible scores range from 0 to 72. Change = end of intervention score - baseline score

  2. Change from baseline in depressive symptoms on the PHQ-9 after the intervention

    Time frame: Baseline and Week 2

    The PHQ-9 is a validated self-report instrument assessing depressive symptoms. Possible scores range from 0 to 27.

    Change = end of intervention score - baseline score

  3. Change from baseline in anxiety symptoms on the GAD-7 after the intervention

    Time frame: Baseline and Week 2

    The GAD-7 is a validated self-report instrument assessing anxiety symptoms. Possible scores range from 0 to 21.

    Change = end of intervention score - baseline score

Secondary outcomes

  1. Change from baseline in experiential avoidance on the EAQ after the intervention

    Time frame: Baseline and Week 2

    The EAQ is a validated self-report instrument assessing experiential avoidance. Possible scores range from 15 to 90.

    Change = end of intervention score - baseline score

  2. Change from baseline in cognitive distortions on the OBQ-44 after the intervention

    Time frame: Baseline and Week 2

    The OBQ-44 is a validated self-report instrument assessing cognitive distortions in OCD. Possible scores range from 7 to 308.

    Change = end of intervention score - baseline score

  3. Change from baseline in uncertainty intolerance on the IUS after the intervention

    Time frame: Baseline and Week 2

    The IUS is a validated self-report instrument assessing intolerance of uncertainty. Possible scores range from 27 to 135.

    Change = end of intervention score - baseline score

  4. Change from baseline in resilience on the RSA after the intervention

    Time frame: Baseline and Week 2

    The RSA is a validated self-report instrument assessing resilience in adults. Possible scores range from 43 to 215.

    Change = end of intervention score - baseline score

Other outcomes

  1. Change from baseline in life quality on the WHOQOL-BREF after the intervention

    Time frame: Baseline and Week 2

    The WHOQOL-BREF is a validated self-report instrument assessing life quality in adults.

    Change = end of intervention score - baseline score

  2. Change from baseline in irrationality on the ATQ after the intervention

    Time frame: Baseline and Week 2

    The ABS-AV is a validated self-report instrument assessing irrationality in adults. Possible scores range from 24 to 120 Change = end of intervention score - baseline score

  3. Change from baseline in global health on the GHQ-12 after the intervention

    Time frame: Baseline and Week 2

    The GHQ-12 is a validated self-report instrument assessing global health in adults.

    Possible scores range from 0 to 36. Change = end of intervention score - baseline score

Study contacts

Contact information is provided by the study sponsor or research team.

Roxana Cardoș, PhD

CONTACT

[email protected]

0040751477323

Sponsors and collaborators

Lead sponsor

Babes-Bolyai University

Other

Collaborators

  • Romanian National Authority for Scientific Research

Registry information

Official study title

The Efficacy of an OCD Prevention Programme for at Risk Adults: a Randomized Clinical Trial

Acronym: ØCD

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Feb 16, 2024
Registry last updated
Apr 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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